Clinical bioinformatics provides biological and medical information to allow for individualized healthcare. In this review, we describe the uses of clinical bioinformatics. After the analysis of the complete human genome sequences, clinical bioinformatics enables researchers to search online biological databases and use the biological information in their medical practices. The data obtained fr...

The Bioinformatics Links Directory continues its collaboration with Nucleic Acids Research to collaboratively publish and compile a freely accessible, online collection of tools, databases and resource materials for bioinformatics and molecular biology research. The July 2011 Web Server issue of Nucleic Acids Research adds an additional 78 web server tools and 14 updates to the directory at htt...

Bioinformatics tools are being developed at a rapid pace in Israel. Universities may have a listing of the tools that were developed in that university, as, for example, the Made-In-Weizmann site 1 developed by Dr Jaime Prilusky, whose assistance to us was invaluable. However, until now there has been no central national repository that made these tools available to researchers. Such a reposito...

We argue the significance of a fundamental shift in bioinformatics, from in-the-small to in-the-large. Adopting a large-scale perspective is a way to manage the problems endemic to the world of the small-constellations of incompatible tools for which the effort required to assemble an integrated system exceeds the perceived benefit of the integration. Where bioinformatics in-the-small is about ...

Databases and chemo- and bioinformatics tools that contain genomic, proteomic and functional information have become indispensable for antimicrobial drug research. The combination of chemoinformatics tools, bioinformatics tools and relational databases provides means of analyzing, linking and comparing online search results. The development of computational tools feeds on a diversity of discipl...

Covering: 2000 to 2016Progress in synthetic biology is enabled by powerful bioinformatics tools allowing the integration of the design, build and test stages of the biological engineering cycle. In this review we illustrate how this integration can be achieved, with a particular focus on natural products discovery and production. Bioinformatics tools for the DESIGN and BUILD stages include tool...

Bioinformatics is the field dedicated mainly to the development and use of computational methods and tools for the understanding of biological data and information, and holds great promise for poverty alleviation and disease control. Developed countries have invested generously in the research and development of bioinformatics. Developing countries must follow suite. These countries should setu...

To access up-to-date biological data sources across multiple heterogeneous databases and analysis tools distributed all over the networks, and to combine them into workflows, we propose a grid-based system for integrating bioinformatics applications, which we named “Bioinformatics: Ask Any Questions (BAAQ)”. BAAQ allows scientists to store and manage biological data and bioinformatics tools as ...

Single cell genomics is a rapidly growing field with many new techniques emerging in the past few years. However, few bioinformatics tools specific for single cell genomics analysis are available. Single cell DNA/RNA sequencing data usually have low genome coverage and high amplification bias, which makes bioinformatics analysis challenging. Many current bioinformatics tools developed for bulk ...

The merger of computer science, mathematics, and life sciences has brought about the discipline known as bioinformatics. However, the transmission (e.g. training, learning, and teaching) of this knowledge becomes an important issue. Many tools have been developed to help the bioinformatics community with that transmission challenge. When selecting the best of these tools, called here BKTMS (Bio...