There has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and function relationship. The bioavailability, metabolism, and biological activity of flavonoids depend ...

Two natural flavonoids, quercetin and isorhamnetin 3-O-acylglucosides, were examined for their inhibitory influence on the in vitro production and release of reactive oxygen species in polymorphonuclear neutrophils (PMNs). The generation of superoxide radical, hydrogen peroxide and hypochlorous acid were measured by, respectively, cytochrome c reduction, dichlorofluorescin oxidation and taurine...

Autosomal dominant Alzheimer's disease (ADAD) is a small subset of Alzheimer's disease that is genetically determined with 100% penetrance. It provides a valuable window into studying the course of pathologic processes that leads to dementia. Arterial spin labeling (ASL) MRI is a potential AD imaging marker that non-invasively measures cerebral perfusion. In this study, we investigated the rela...

Dopaminergic signaling is one of the regulatory pathways being investigated for its implication in glucose metabolism. The aim of this study was to determine the effect of cabergoline on biochemical and anthropometric parameters in prediabetes stage (impaired fasting glucose and impaired glucose tolerance). In this double blind, placebo-controlled, pilot study, 27 prediabetic adults were random...

Introduction and Aim:The atherosclerosis is the major cause of morbidity mortality among diabetes population. Diabetes mellitus can accelerate atherosclerotic processes. Adenosine deaminase (ADA) plays a significant role in both glucose lipid metabolism through adenosine. This study aimed to correlate index with adenosine levels Type 2 patients. The aim find association between serum ADA index....

BACKGROUND Greater red meat intake is associated with an increased type 2 diabetes and cardiovascular disease risk. However, the relation of red meat intake to biomarkers of inflammation and glucose metabolism has not been investigated thoroughly. OBJECTIVE We hypothesized that greater red meat intake would be associated with biomarkers of inflammation and glucose metabolism, which would be p...

Biomarkers are early predictors of various disorders, circulating level C-reactive protein is a sensitive biomarker systemic inflammation and may also be associated with the development diabetic, hepatic, cardiovascular diseases. In present study, we aimed to investigate association between levels high (hs-CRP) biomarkers for health. The retrospective analysis included 438 individuals who were ...

the neuregulin is a member of the epidermal growth factors (egf) family of receptor kinases, was originally identified as the product of the transforming gene derived from chemically induced rat neuroblastoms. a variety of different protein isoforms are produced from single neuregulin gene. four distinct vertebrate gene encode neuregulin, prosaically named nrg1, nrg2, nrg3, and nrg4. most of bi...