Circulating tumor cells (CTCs) have been considered as the origin of cancer metastasis. Thus, detection of CTCs in peripheral blood is of great value in different types of solid tumors. However, owing to extremely low abundance of CTCs, detection of them has been technically challenging. To establish a simple and efficient method for CTCs detection in patients with hepatocellular carcinoma (HCC...

An explicit finite-difference scheme is presented for solving the two-dimensional Biot equations of poroelasticity across the full range of frequencies. The key difficulty is to discretize the Johnson-Koplik-Dashen (JKD) model which describes the viscous dissipations in the pores. Indeed, the time-domain version of Biot-JKD model involves order 1/2 fractional derivatives which amount to a time ...

We present two multiscale reaction-diffusion (RD) systems modeling sulfate attack in concrete structures (here: sewer pipes). The systems are posed on two different spatially separated scales. The only difference between them is the choice of the micro-macro transmission condition. We explore numerically the way the macroscopic Biot number Bi connects the two reactiondiffusion scenarios. We ind...

Purpose Due to the rapid growth of blockchain technology in recent years, fusion and Internet Things (BIoT) has drawn considerable attention from researchers industrial practitioners is regarded as a future trend technological development. Although several authors have conducted literature reviews on topic, none examined development knowledge structure BIoT, resulting scattered research (R&...

A year ago, the author evolved a simulated artificial creature (biot, i.e. biological robot), called LIZZY, which consisted of fully connected neural network modules (called GenNets), whose weights were evolved such that each GenNet performed some desired behavior, such as making the biot walk straight ahead, turn clockwise or anticlockwise, peck, or mate [de Garis 1990, 1991, 1993]. Other such...

We characterized the poroelastic deformation of six cores from three formations associated with the Bakken play in the Williston Basin (the Lodgepole, Middle Bakken, and Three Forks formations). All are low-porosity, low-permeability formations, but vary considerably in clay, kerogen, and carbonate content. The experimental program simulated reservoir stress changes associated with depletion an...

A three-dimensional fully-coupled poroelastic displacement discontinuity method is developed and used to analyze the temporal variation of opening and slip of a natural fracture in a reservoir in response to the sudden application of fluid pressure in the fracture surfaces. Numerical results show that a hydraulic fracture opens in an increasing manner with time as the rock moves towards a drain...

The generalized Biot-Brinkman equations describe the displacement, pressures and fluxes in an elastic medium permeated by multiple viscous fluid networks can be used to study complex poromechanical interactions geophysics, biophysics other engineering sciences. These extend on Biot multiple-network poroelasticity one hand Brinkman flow models hand, as such embody a range of singular perturbatio...

As many large-scale enterprise information systems start to utilize P2P networks, parallel, grid, cloud and Internet computing, they have become a major source of business information. Techniques and methodologies to extract quality information in distributed systems are of paramount importance for many applications and users in the business community. Data mining and knowledge discovery play k...