BACKGROUNDS Several domains of cognitive function, including learning memory and executive function, are impaired in mood disorders. Also, the relationship between disturbances of these two cognitive domains has been suggested. In line with the recent initiative to establish a standard measure of cognitive decline in bipolar disorder, the present study was conducted to (1) test the criterion-re...

OBJECTIVES To examine the feasibility of collecting course of illness data from patients with bipolar I and II disorder, using weekly text-messaged mood ratings, and to examine the time trajectory of symptom ratings based on this method of self-report. METHODS A total of 62 patients with bipolar I (n = 47) or II (n = 15) disorder provided mood data in response to weekly cell phone text messag...

OBJECTIVE Migraine is a common comorbidity of bipolar disorder and is more prevalent in women than men. We hypothesized comorbid migraine would be associated with features of illness and psychosocial risk factors that would differ by gender and impact outcome. METHOD A retrospective analysis was conducted to assess association between self-reported, physician-diagnosed migraine, clinical vari...

Although twin and adoption show bipolar disorder (BP) has a strong genetic component, few chromosomal regions have been consistently implicated by molecular genetic studies. To address this issue, we sought to determine if quantitative dimensions of bipolar disorder symptoms would be useful for detecting genes that underlie the susceptibility to bipolar disorder. Subjects were 520 individuals d...

background lithium is a drug for treatment of bipolar disorder by correcting mania and reducing depressive mood swings. objectives in this study, effects of lithium on volumetric parameters of cerebellum were investigated using stereological methods. materials and methods in this experimental study, 20 sexually mature wistar male rats were selected and divided in two groups randomly (n = 10). a...

ôbjective: the mood disorder questionnaire (mdq) has been designed as a screening self-report inventory for diagnosing bipolar mood disorders. this study investigated the validity and the optimal cut-off threshold of the persian version of mdq in a group of ïranian depressive patients. methods: ône hundred and twenty patients with probable diagnosis of mood disorders attending psychiatric clini...

Most of the existing data on real-life management of bipolar disorder are from studies conducted in western countries (mostly United States and Europe). This multinational, observational cohort study aimed to describe the management and clinical outcomes of bipolar patients in real-life conditions across various intercontinental countries (Bangladesh, Egypt, Iran, Israel, Tunisia, and Ukraine)....

OBJECTIVE CHRNA7 has been shown to be a strong candidate gene for schizophrenia and bipolar disorder. It is located on chromosome 15q13-q14, which is one of the replicated linkage spots for schizophrenia and bipolar disorder. METHODS We conducted an association study to determine whether previous positive association is replicable in the Korean population. We included 254 patients with schizo...

Even though neurofibromatosis ( NF) is not a rare neurological disorder, but there is few studies regarding  the relationship between  NF and psychological disorders. A 14 year old girl with NF type 1 associated  with multiple cerebral lesions was admitted in psychiatric ward due to restlessness , hypertalktiveness aggressive behavior, and flight of idea. Psychiatric diagnosis, based on DSM IV ...