Background: Bitter leaf and palm oil combination in treating diarrhoea is common Africa. The aim of this study to determine the synergistic antimicrobial potential Vernonia amygdalina Elaeis guineensis on bacteria isolates from diarrheic stool.
 Methodology: One hundred fifty (150) stool samples Diagnostic Laboratory Rivers State University Teaching Hospital (RSUTH), Port Harcourt, were in...

Based on the molecular findings that many bitter taste receptors (T2Rs) are expressed within the same receptor cells, it has been proposed that bitter taste is encoded by the activation of discrete neural elements. Here we examined how a variety of bitter stimuli are represented by neural activity in central gustatory neurons. Taste responses (spikes/s) evoked by bathing the tongue and palate w...

The ability to taste bitterness evolved to safeguard most animals, including humans, against potentially toxic substances, thereby leading to food rejection. Nonetheless, bitter perception is subject to individual variations due to the presence of genetic functional polymorphisms in bitter taste receptor (TAS2R) genes, such as the long-known association between genetic polymorphisms in TAS2R38 ...

background & aim: the fruit of citrullus colocynthis has a bitter taste and antibacterial properties against pathogen factors.the aim of current research was to study the effects of different dietary level of bitter cucumber fruit powderwith and without protexin probiotic supplementation on growth performance, carcass traits and intestinal morphology of broiler chicks. experimental: two hundred...

The recent discovery of mammalian bitter, sweet, and umami taste receptors indicates how the different taste qualities are encoded at the periphery. However, taste representations in the brain remain elusive. We used a genetic approach to visualize the neuronal circuitries of bitter and sweet tastes in mice to gain insight into how taste recognition is accomplished in the brain. By selectively ...

The aim of this study was to synthesize chemically activated carbons from different agricultural residues, i.e., pistachio shell (PS), bitter orange peel (OP), and saffron petal (SP), subsequently use them as supports for loading a Ni catalyst. Supercritical water gasification bio-oil applied investigate the catalytic performance resulting catalysts. physicochemical properties carbon (ACs) cata...

Bitter taste stimuli are detected by a diverse family of G protein-coupled receptors (GPCRs) expressed in gustatory cells. Each bitter taste receptor (TAS2R) responds to an array of compounds, many of which are toxic and can be found in nature. For example, human TAS2R16 (hTAS2R16) responds to β-glucosides such as salicin, and hTAS2R38 responds to thiourea-containing molecules such as glucosino...

Apple growers, private consultants, and extension specialists have all noted that bitter rot is increasingly common and is causing sporadic but economically significant losses throughout the northeastern and north central apple growing regions of North America. Forty years ago, bitter rot was considered a “southern disease” and apples with bitter rot were rarely observed in northern production ...

Treatment compliance is reduced when pharmaceutical compounds have a bitter taste and this is particularly marked for paediatric medications. Identification of bitter taste liability during drug discovery utilises the rat in vivo brief access taste aversion (BATA) test which apart from animal use is time consuming with limited throughput. We investigated the suitability of using a simple, non-a...