Plasma soluble Receptor for Advanced Glycation End-products (sRAGE) is a strong marker of vascular outcomes although evidence on the direction of association is mixed. Compared to whites, blacks have lower levels of sRAGE. We hypothesized that genetic determinants of sRAGE would help clarify the causal role of sRAGE and the black-white difference in sRAGE levels. We conducted a genome-wide anal...

BACKGROUND AND PURPOSE This study was conducted to determine if blacks hospitalized for cerebrovascular events had more severe cerebrovascular events than whites similarly hospitalized. METHODS Data from the Maryland Health Services Cost Review Commission were used to determine incidence of coma, death rates, age at death of those who died, and length of stay for acute hemorrhagic and occlusi...

Prostate cancer is the most common malignancy in US men (more than 165,000 cases per annum) and occurs substantially more frequently in blacks than in whites. The causes of this disease are, however, poorly understood. Alcohol consumption, which has been clearly related to malignancies of the upper aerodigestive tract, may also increase risk of cancer at other sites, including the prostate. The...

BACKGROUND Despite the impressive decline in coronary heart disease death rates, a mortality differential between blacks and whites persists. Our study objective was to determine whether excess mortality among well-controlled hypertensive black men compared with whites is due to differences in disease incidence or in case fatality. METHODS AND RESULTS Of 3382 male subjects (1266 blacks and 21...

INTRODUCTION The objective of this study was to examine the racial disparities in total ankle arthroplasty (TAA) utilization and outcomes. METHODS We used the National Inpatient Sample (NIS) to study the time-trends. Race was categorized as White and Black. Utilization rates were calculated for the U.S. general population per 100,000. Hospital length of stay, discharge disposition and mortali...

BACKGROUND Life expectancy is shorter and mortality from cardiovascular disease higher among blacks than among whites in the United States. We studied whether place of birth was associated with mortality from cardiovascular causes among non-Hispanic black and white residents of New York City. METHODS We linked mortality records from 1988 through 1992 with 1990 U.S. census data for New York Ci...

In this paper, I examine 1960 to 1980 trends in suburbanization and education segregation within the black and white populations of four U.S. metropolitan areas. This analysi s provides a test of Wilson’s (1987) social isolation thesis which claims that, during the 1960s and 1970s, middle-class black s moved out of inner-city ghettos into suburbs, thereby isolating themselves from lower-class b...

It has been believed that differences in dental caries experience exist between whites and blacks, and between persons living in southern and northern states. Blacks have been reported to have lower caries experience than whites.' Caries experience of blacks in the North is similar to that of whites in some reports,2'3 but in the South, caries experience of whites often has been reported as twi...

BACKGROUND AND PURPOSE Blacks have an excess burden of stroke compared with whites; however, data comparing ischemic stroke subtypes among the 2 groups are limited and typically involve relative frequencies. The objective of this study is to compare the incidence rates of ischemic stroke subtypes between blacks and whites within a large, representative, biracial population. METHODS The Greate...