When aiming to produce a target chemical at high yield, titer, and productivity, various combinations of genetic parts available to build the target pathway can generate a large number of strains for characterization. This engineering approach will become increasingly laborious and expensive when seeking to develop desirable strains for optimal production of a large space of biochemicals due to...

Microorganisms reside in diverse environmental communities where interactions become indispensable due to close physical associations. These are driven by chemical communication among different microbial kingdoms, particularly between fungi and bacteria. Knowledge about these signals provides useful information the nature of allows predictions community development environments. Here, we provid...

Background & Aim: Continuous use of antibiotics leads to drug resistance and thereby to a reduced efficacy of the drugs. Antibiotics accumulate in the environment and fish pose a potential risk to consumers and to the environment.Increased public awareness of the negative effects caused by overexposure to synthetic chemicals has led to the search for ‘‘green drugs’’, such as organic and synthet...

Background and Purpose. Dry needling is an effective therapy for the treatment of pain associated with myofascial trigger point (MTrP). However, the biochemical effects of dry needling that are associated with pain, inflammation, and hypoxia are unclear. This study investigated the activities of β-endorphin, substance P, TNF-α, COX-2, HIF-1α, iNOS, and VEGF after different dosages of dry needli...