BACKGROUND Salvia mirzayanii, a native plant to Iran, is shown to have immunomodulatory effects on lymphocyte proliferation. OBJECTIVE To identify the bioactive immunomodulatory compound(s) present in S. mirzayanii. METHODS The crude extract was fractionated to five fractions in two steps using different solvents. The fractions were subjected to bioassay-guided fractionation. All the fracti...

1. The lipid fluidity of three major rat liver plasma-membrane subfractions, as well as Golgi apparatus and endocytic fractions, was assessed with a fatty acid spin probe by using e.s.r. techniques. 2. The sinusoidal (blood-facing) plasma-membrane subfraction was the most fluid of the three plasma-membrane regions. Fractions originating from the bile-canalicular and contiguous (lateral) regions...

In this study, we examined in vitro the bio-activity of peptide fractions obtained from soybeans against blood (CCRF-CEM and Kasumi-3), breast (MCF-7), and prostate (PC-3) cancer cell proliferation. Gastro-intestinal treated peptide fractions (<5, 5-10 and 10-50 kDa) prepared from seed proteins of two high oleic acid soybean lines-N98-4445A, S03-543CR and one high protein line-R95-1705, were te...

Carp erythrocytes were fractionated by angle-head centrifugation which yielded fractions with a linear increase in density. Haematological examinations revealed that the heavier red blood cells of carp had greater volumes (MCV), more haemoglobin (MCH) and higher haemoglobin concentrations (MCHC) than light ones. The same experiments with human red cell fractions yielded a decrease in MCV, const...

Rural dwellers in Nigeria often resort to herbal remedy and dietary control in the treatment of diabetes mellitus (DM). This work was undertaken to provide the rationale for the use of the leaves of Gogronema latifolium as a traditional antidiabetic agent. Methanol extract (ME) of the leaves of G. latifolium was prepared by soxhlet extraction while the aqueous extract (AE) was prepared by cold ...

Normal human peripheral blood lymphocytes were separated on discontinuous gradients of 17-35% bovine serum albumin (BSA) into nine fractions. Three subpopulations of lymphocytes were obtained. One occupies the top third of the gradient (fractions 1-3, 17-23% BSA) and is rich in cells characterized by a high spontaneous rate of DNA synthesis and by the ability to give rise to colony-forming unit...

BACKGROUND Carbon tetrachloride (CCl4) is a potent nephrotoxin, as it causes acute as well as chronic toxicity in kidneys. Therefore, this study was carried out to assess the pharmacological potential of different fractions of Carissa opaca fruits on CCl4-induced oxidative trauma in the kidney. METHODS The parameters studied in this respect were the kidney function tests viz, serum profile, u...

this study investigated the effect of season (wet and dry) on milk composition of the dromedary camel (camelus dromedarius). milk samples representing the wet and dry seasons were analyzed for total solids (ts), fat (f), solids-non-fat (snf), ash, crude protein (cp), nitrogen soluble at ph 4.6 (sn), mineral content (mc) and casein fraction (cnf). camel milk had higher (p<0.05) fat content in th...

background: acanthamoeba keratitis (ak) is potentially a sight-threatening infection and its treatment is challenging. this is mainly due to presence of resistant cyst form. indeed, cysts are highly resistant to current available drugs. chemical drugs are toxic to human keratocytes. it should also be mentioned that most available anti- acanthamoeba drugs are poorly cysticidal, in iran and world...

  Objective(s): Echis carinatus is one of the venomous snakes in Iran. The venom of Iranian Echis carinatus is a rich source of protein with various factors affecting the plasma protein and blood coagulation factor. Some of these proteins exhibit types of enzymatic activities. However, other items are proteins with no enzymatic activity.   Materials and Methods: In order to study the mechanism ...