To the Editor: The review—“Brachial vs. Central Systolic Pressure and Pulse Wave Transmission Indicators: A Critical Analysis”—by Dr Izzo1 provided a broad overview of physiology and clinical consequences of pulse wave transmission in the human arterial system. We contend that a “critical analysis” of literature in this field should include consideration of all plausible evidence on the physiol...

The central nervous system (CNS) is a perfectly regulated environment with conditions far different from those in the rest of the organism. Even slight changes in this machinery affect its functioning. The blood-brain barrier (BBB) is the frontier that isolates brain tissues from the substances circulating in the blood vascular system. It is also a diffusion barrier that allows only water and s...

The initial distribution volume of glucose (IDVG) can be calculated from the arterial plasma glucose level between 3 and 7 min after a bolus intravenous infusion of 5 g glucose. Ishihara and colleagues have investigated the value of IDVG over the past decade. Although IDVG is simple and cheap to measure, there have been several very different proposals regarding what it should be used for. The ...

A. 緒 言 これまで,臨 床血液学の主流は形態学的研究に あ り,血 液の呼吸生理学的役割については必ずし も十分な理解が持たれていたとは思えない.わ た くしは昭和42年10月,新 潟における第7回 日本胸 部疾患学会の特別講演において,血 液ガスをめぐ る二,三 の問題点について述べたが,本 日は血液 そのものの呼吸生理学的な役割について報告 した いと思 う. 呼吸生理からみた血液の役割は,肺 と組織 との 間の呼吸ガスの運搬,な らびに諸臓器の機能を発 揮するに適した生体内環境を維持す る作用とに要 約できる.そ のために,血 液そのものの物理 ・化 学的性状 と調和した神経活 ・体液活調節の機序に よつて,外 界からの環境条件の影響をやわらげ, 生体をして常に正常な機能を発揮 しやすい状態に おく. 呼吸生理学の歴史をひもとくとき,今 世紀に入 つてからの発展はまことに目...

Competition is a natural part of human nature. Techniques and substances employed to enhance athletic performance and to achieve unfair success in sport have a long history, and there has been little knowledge or acceptance of potential harmful effects. Among doping practices, blood doping has become an integral part of endurance sport disciplines over the past decade. The definition of blood d...

Physiology is often considered a challenging course for students. It is up to teachers to structure courses and create learning opportunities that will increase the chance of student success. In an undergraduate exercise physiology course, concept maps are assigned to help students actively process and organize information into manageable and meaningful chunks and to teach them to recognize the...

New methods in molecular biology and genetics have made possible many of the dramatic advances in physiological research that have occurred in recent years. For those of us who spend most of our time in the research laboratory, it si sometimes difficult to avoid a research-oriented, reductionist mind-set when discussing physiology with students. This article illustrates, with a few examples, th...

Carter JR, West JB. Space physiology within an exercise physiology curriculum. Adv Physiol Educ 37: 220 –226, 2013; doi:10.1152/advan.00035.2013.—Compare and contrast strategies remain common pedagogical practices within physiological education. With the support of an American Physiological Society Teaching Career Enhancement Award, we have developed a junioror seniorlevel undergraduate curricu...