Ulcerative colitis (colitis ulcerosa) is a non-specific inflammatory bowel disease of unknown etiology. The symptoms which are observed in the course of ulcerative colitis are: an increase in the number of leukocytes and blood platelets, an increase in the concentration of IL-6 and anemia. Blood platelets are the key element, linking the processes of hemostasis, inflammation and the repair of d...

BACKGROUND Sphingolipids are signaling molecules in a range of biological processes. While sphingosine-1-phosphate (S1P) is thought to be abundantly stored in platelets and released upon stimulation, knowledge about the distribution and function of other sphingolipids in blood is lacking. OBJECTIVES To analyze the sphingolipid content of blood components with special emphasis on dynamic chang...

As a young microscopist in 1874, William Osler was probably the first physician to recognize platelets in blood as a single unit and their coalescence when blood was shed. He expounded on the earlier observations of Schultze, who in 1865 noted abundant, irregular masses of colorless globules in normal blood that were almost certainly platelets. The impact of Osler's initial observations were di...

1. Under normal circumstances blood platelets are largely derived from the megakaryocyte of the blood-forming organs. 2. The transitional leucocyte, representing a persistent form of the embryonic premegakaryocyte, is a circulating homologue of the megakaryocyte and probably plays some part in normal platelet formation. 3. Under conditions of excessive demand for platelet production, there may ...

Introduction: Pseudo thrombocytopenia (PTP) is a phenomenon of falsely low platelet counts obtained on Hematology Analyzers (HA) due to in vitro platelet clumping in the presence of anticoagulants. Methods: Papers on the subject of pseudothrombocytopenias eff ects were searched for in biomedical journals indexed in MEDLINE from 1969 to 2016. All other thrombocytopenia types were not analyzed. T...

T relationship among platelet survival, vessel injury, and thrombosis is of interest because of the role that platelets play in the development of atherosclerosis and its thromboembolic complications. Blood platelets do not adhere to normal endothelium. However, when a blood vessel is injured, platelets adhere to the injury site and, if blood flow is disturbed, thrombi can form on the injured a...

Systemic sclerosis (SSc) is characterized by a progressive fibrosis of the perivascular and interstitial connective tissues which can involve the skin, heart, lungs, kidneys, and the gastrointestinal tract. SSc is an uncommon, debilitating condition, associated to a vital risk linked to visceral extensions and has a high case-fatality rate among connectivitis. SSc begins in the vast majority of...

T relationship among platelet survival, vessel injury, and thrombosis is of interest because of the role that platelets play in the development of atherosclerosis and its thromboembolic complications. Blood platelets do not adhere to normal endothelium. However, when a blood vessel is injured, platelets adhere to the injury site and, if blood flow is disturbed, thrombi can form on the injured a...

This study was carried out to evaluate the relationship between narghile smoking and serum concentration of serotonin endorphin some blood hematological indices in males. Group smokers composed 50 voluntary, control group 36 healthy voluntary. conducted on adults man that ages (18-25 years). The markers measured this were (platelets, hematocrit, hemoglobin, white cells).
 showed a signific...