A new method for determining absolute left ventricular (LV) volumes from radio nuclide gated blood pool images has been validated at our institution (1). Only four parameters are needed to determine LV volumes: the LV count rates from an LAO and an RPO image (180° opposed to the LAO), a venous blood sample, and a patient thickness measurement. The procedure can easily be performed as a part of ...

Magnetic resonance angiography (MRA) is an imaging method to examine blood vessels based on the magnetic resonance imaging (MRI) technique. For this purpose, blood pool contrast agents have been developed to selectively increase the signal intensity of the intravascular lumen for improvement of the contrast-to-noise ratio in MR images. Here, we describe the design and the syntheses of six novel...

BACKGROUND AND PURPOSE Time-resolved MRA with the use of bolus injection of paramagnetic agents has proved valuable in neurovascular imaging. Standard contrast agents have limited blood-pool residence times, motivating the development of highly protein-bound blood-pool agents with greater relaxivity and longer intravascular residence, affording improved image quality at lesser doses. This study...

Magnetic particle imaging (MPI) is a new medical imaging approach that is based on the nonlinear magnetization response of super-paramagnetic iron oxide nanoparticles (SPIOs) injected into the blood stream. To date, real-time MPI of the bolus passage of an approved MRI SPIO contrast agent injected into the tail vein of living mice has been demonstrated. However, nanoparticles are rapidly remove...

BACKGROUND Cerebral blood flow (CBF) quantitation using technetium-99m hexamethylpropyleneamine oxime (99mTc-HMPAO) generally requires assessment of input function by arterial blood sampling, which would be invasive for small animals. We therefore performed chest dynamic planar imaging, instead of arterial blood sampling, to estimate the input function and establish noninvasive quantitation met...

Two cases of heptatic hemangioma are reported in which multiple-radionuclide and ultrasound techniques were combined in the diagnostic process. Blood pool imaging rather than perfusion imaging proved to be the most definitive diagnostic procedure. The application of radionuclide and ultrasound studies in the differential diagnosis of focal lesions of the liver is discussed.

Background Cardiac MR has begun to be utilized for imaging ablation lesions. Peri-procedural imaging could potentially be used to guide therapy, but this application has unique requirements and limitations. In peri-procedural imaging of acute lesions, subjects are frequently sedated and imaging should be conducted free-breathing. Furthermore, Late Gadolinium Enhancement (LGE) imaging of sub-end...

Department of Nuclear Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC Nuclear Medicine Service, Veterans Administration Medical Center / Department of Diagnostic Radiology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA Gastrointestinal Section, Veterans Administration Medical Center / Department of Internal Medicine, College o...