Male rabbits received 20 micrograms/ml of cadmium in drinking water for nine months. At the end of the treatment aortic vascular resistance was increased, whereas maximum rate of increase in left ventricular pressure, aortic blood flow, stroke volume, cardiac output, left ventricular minute work, and left ventricular stroke work were reduced. Arterial blood pressure, heart rate, and the index o...

The present study was performed to determine whether sympathetic outflow and arterial blood pressure in water-deprived rats are dependent on the ongoing neuronal activity of the hypothalamic paraventricular nucleus (PVN). Renal sympathetic nerve activity (RSNA), mean arterial blood pressure (MAP), and heart rate were recorded in urethane-alpha-chloralose-anesthetized rats that were deprived of ...

BACKGROUND Epinephrine (EPI) is an important neurotransmitter and hormone. Its role in regulating cardiovascular function at rest and with stress is unclear, however. METHODS AND RESULTS An epinephrine-deficient mouse model was generated in which the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase was knocked out (KO). Blood pressure and heart rate were monitored by tel...

background: use of single measurement of risk factors can distort their estimated effects, due to random error in measurements. the aim of this study was to examine the extent of underestimation in the estimated effect of common variables in physical exam i.e. systolic and diastolic blood pressure (sbp, dbp) and body mass index (bmi) on cardiovascular diseases in tehran lipid and glucose study ...

Reflexogenic control of vascular capacity was studied by measuring the mean circulatory pressure (PMc) a t various blood volumes. PMC was obtained by fibrillating the heart for 10 seconds and rapidly transferring blood from the aorta to the vena cava until the pressures equilibrated. It was measured 0.5, 2, and 5 minutes after randomized changes in blood volume of 0 to ± 30% of the control volu...

BACKGROUND Chronic lead exposure causes hypertension and cardiovascular disease. Our purpose was to evaluate the effects of acute exposure to lead on arterial pressure and elucidate the early mechanisms involved in the development of lead-induced hypertension. METHODOLOGY/PRINCIPAL FINDINGS Wistar rats were treated with lead acetate (i.v. bolus dose of 320 µg/Kg), and systolic arterial pressu...

background tracking of blood pressure from early life to adulthood and the increasing prevalence of elevated blood pressure in the pediatric age group are considered as important health issues. rapid lifestyle change and dietary habits are considered as important determinants of this problem. this study aimed to systematically review the studies on the association of dietary habits and blood pr...

this study was conducted to investigate the effects of brewer's yeast supplementation on serum lipoproteins and blood pressure in patients with type 2 diabetes mellitus.in a randomized double blind clinical trial, 90 adults with type 2 diabetes mellitus were recruited, and divided randomly into 2 groups, trial group received brewer's yeast (1800 mg/day) and control group received placebo for 12...

Central administration of acetylcholine or nicotine to rats induces changes in blood pressure and heart rate via central chol inoceptor activation (1, 2). Physostigmine a cholinesterase inhibitor also modifies blood pressure and heart rate (3, 4). Thus, central cholinergic mechanisms may be physio logically involved in the central control of cardiovascular function. In the present experiments, ...