Obsessive-compulsive disorder (OCD) is achronic psychiatric disorder characterized by recurrent intrusive thoughts and/or repetitive compulsory behaviors. This psychiatric disorder is known to be stress responsive, as symptoms increase during periods of stress but also because stressful events may precede the onset of OCD. However, only a few and inconsistent reports have been published about t...

Psychogenic excoriation (PE), characterized by excessive scratching or picking of the skin, is not yet recognized as a symptom of a distinct DSM-IV disorder. It is a chronic disorder with a high rate of psychiatric comorbidity. The purpose of this study was to compare patients diagnosed with PE and patients with another dermatological disease in terms of comorbid psychiatric disorders. Thirty-o...

The treatment recommendations in obsessive-compulsive disorder (OCD) after lack of response to selective serotonin reuptake inhibitors (SSRIs) include augmentation with other drugs, particularly clomipramine, a more potent serotonin reuptake inhibitor (SRI), or antipsychotics. We present two cases of response to lamotrigine augmentation in treatment-refractory OCD; each received multiple SRI tr...

UNLABELLED Around 7%-10% of patients with obsessive-compulsive disorder (OCD) are refractory to first-line treatment. Neurosurgical approaches are available such as capsulotomy or deep-brain stimulation (DBS). There is strong evidence for central involvement of the corticostriatopallidothalamocortical (CSPTC) circuit in OCD, but the exact mechanism through which these interventions lead to clin...

Background: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric worldwide. Inadequate response of OCD patients to usual agent makes this great challenge, and recent studies have recommended augmentation therapy as new choice. Objectives: As traces noradrenergic dysfunction been noted in pathophysiology, the current study aimed assess efficacy clonidine for treating OCD. Methods: Th...

background and aim: the aim of this research was study the effectiveness of  group cognitive- behavior therapy on reducing  body dysmorphic disorder and inter personal sensitivity among high school girls in ahvaz city. methods: the first sample included 800 students who were selected with  multi­ stage random sampleing and completed y-bocs-bdd and inter personal sensitivity  subscale of  scl-90...

CONTEXT The empirical literature on treatment of obsessive-compulsive disorder (OCD) in children and adolescents supports the efficacy of short-term OCD-specific cognitive-behavior therapy (CBT) or medical management with selective serotonin reuptake inhibitors. However, little is known about their relative and combined efficacy. OBJECTIVE To evaluate the efficacy of CBT alone and medical man...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...