CONTEXT Children with meningitis are routinely admitted to the hospital and administered broad-spectrum antibiotics pending culture results because distinguishing bacterial meningitis from aseptic meningitis is often difficult. OBJECTIVE To develop and validate a simple multivariable model to distinguish bacterial meningitis from aseptic meningitis in children using objective parameters avail...

aseptic meningitis or benign lymphocytic meningitis has been given. Wallgren (1925) gave the first account of this condition. His observa, tions were based on a small epidemic. Since then it has been described from time to time by many physicians under different names ?aseptic benign purulent meningitis (Schiff, 1930), idiopathic benign serous, meningitis (Andersen and Wulff, 1930), epidemic me...

OBJECTIVE To evaluate evidence-based data on adjunctive glucocorticoid therapy in central nervous system bacterial infections. DESIGN A literature review of studies, particularly controlled trials, that have evaluated dexamethasone therapy for acute bacterial meningitis and glucocorticoid therapy for tuberculous meningitis. MAIN OUTCOME MEASURES Clinical outcomes were mortality and morbidit...

Nosocomial bacterial meningitis requires timely treatment, but what is difficult is the prompt and accurate diagnosis of this disease. The aim of this study was to assess the potential role of decoy receptor 3 (DcR3) levels in the differentiation of bacterial meningitis from non-bacterial meningitis. A total of 123 patients were recruited in this study, among them 80 patients being with bacteri...

Fibronectin concentrations in the cerebrospinal fluid were assessed in 20 patients with acute meningitis using a turbidimetric immunoassay. A significant increase in fibronectin concentrations was observed in patients with bacterial meningitis; decreased concentrations were observed in patients with viral meningitis. The determination of fibronectin concentration in patients with bacterial meni...

Eosinophilic meningitis is rare and is mainly caused by parasitic infections. Here we described the first case of HSV eosinophilic meningitis.

Background and Objectives: Bacterial meningitis is a medical emergency with a potential for serious neurological damage or even death. Rapid diagnosis is important and henceforth critical for the early intervention by antibiotic therapy to prevent complications. Therefore the aim of the present study was to evaluate CSF ferritin levels in children with different etiologies of meningitis. Materi...

background and aims: since the epidemiological, clinical and experimental characteristics of meningitis are different for various locations, this study was conducted to investigate the characteristics of meningitis patients admitted to hospitals of yazd in the 2009 to 2013. materials and methods: in this cross-sectional and descriptive study, all 261 patients with meningitis were considered in ...

Background Meningitis is a common neurological emergency and a leading cause of death and neurological disability worldwide. MRI is extremely useful for detecting and monitoring the complications of meningitis. The purpose of this study was to describe the brain MRI findings in children with complicated meningitis. Materials and Methods  This cross-sectional study was conducted in Radiology De...

Tuberculous meningitis (TBM) is caused by tuberculosis infection of of the meninges, which are the membrane systems that encircle the brain, with a high morbidity and mortality rate. It is challenging to diagnose TBM among other types of meningitis, such as viral meningitis, bacterial meningitis and cryptococcal meningitis. We aimed to identify metabolites that are differentially expressed betw...