Mutations that lead to drug resistance limit the efficacy of antibiotics, antiviral drugs, targeted cancer therapies, and other treatments. Accurately calculating protein–drug binding affinity changes upon mutations in target is high interest as this can yield a better understanding into how such drive drug-resistance, especially when mutation question does not directly interfere with drug. The...

The hydrological response to land cover changes induced by human activities in arid regions has attracted increased research interest in recent decades. The study reported herein assessed the spatial and quantitative changes in surface runoff resulting from land cover change in the Al-Baha region of Saudi Arabia between 1990 and 2000 using an ArcGIS-surface runoff model and predicted land cover...

We apply the Chapman-Enskog procedure to derive hydrodynamic equations on an arbitrary surface from the Boltzmann equation on the surface.

We consider the flow of a dilute gas around a macroscopic heavy object. The state of the gas is described by an extended Boltzmann equation where the interactions between the gas molecules and the object are taken into account in computing the rate of change of the distribution function of the gas. We then show that the extended Boltzmann is equivalent to the usual Boltzmann equation, supplemen...

in this work x-ray fluorescence (xrf) technique was used to evaluate the soil pollution withheavy metals for twenty four surface soil samples (0–10 cm in depth) from various locations to cover theindustrial area in omdurman city, sudan. concentrations of 10 elements cr, ni, cu, zn, zr, pb, rb, co, cd andas were determined. it was found that cr, cu and cd concentrations for almost all studied si...

ammonium carbonate and ammonium sulfate have been proposed and used as two new fuels for synthesizing gamma alumina nanoparticles. the prepared samples have been characterized by x-ray diffraction (xrd), 2 n  adsorption (bet) and transmission electron microscopy (tem). a comparison has been made between the properties of the nanoparticles synthesized by these two fuels and other conventional fu...

The aim of this research was to accurately measure the surface of the semi lunar articular surface of the pelvis (facies lunata acetabuli) and the variability of the acetabular geometry, as well as to determine the correlation between measured parameters. 30 macerated anatomical specimens of pelvic bones were measured. The radius and depth were measured in the classical way, while cartilaginous...

zinc oxide (zno) nanoparticles were synthesized by spray pyrolysis method using an aqueous solution of zinc acetate at various concentrations from 5 to 25 wt%. the decomposition of precursor solutions was carried out at 800, 1000 and 1200ºc under different atomizing pressures. the crystal structure and morphology of synthesized nanoparticles were characterized by x-ray diffraction (xrd) spectro...

since heavy metals are considered as one of the major pollutants threatening, the main goal of this study was to bring out the concentrations of pb, zn and mn in the surface sediments off bushehr in the persian gulf. for this purpose, after collection of samples, the concentrations of the three metals in surface sediments were measured through the atomic absorption. the results were compared wi...