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To analyze the urinary biomarkers in men with lower urinary-tract symptoms (LUTS) and identify interstitial cystitis/bladder pain syndrome (IC/BPS) from other dysfunctions (LUTDs) by levels of characteristic biomarkers. In total, 198 LUTS were prospectively enrolled urine samples collected before intervention or medical treatment. Videourodynamic studies routinely performed LUTDs diagnosed as h...

Purpose To report our outcomes with the use of a thermo-expandable metallic intraprostatic stent (Memokath) for patients with bladder outlet obstruction (BOO) secondary to prostatic obstruction, and to assess it is a feasible option for many frail and elderly men unsuitable for surgery. Materials and Methods We reviewed patients who underwent insertion of a Memokath stent for BOO over 17 year...

OBJECTIVE To examine rabbit cavernosal smooth muscle (CSM) relaxation to ATP, ADP and UTP in normal rabbits and in models of conditions that predispose to erectile dysfunction (ED), diabetes mellitus (DM; induced for 6 months) and bladder outlet obstruction (BOO, 6 weeks after surgery). MATERIALS AND METHODS Concentration-response curves (CRCs) were constructed to ATP, ADP and UTP on CSM from...

Although evidence shows that urodynamic study may not improve outcomes, it can be used to evaluate men with lower urinary tract symptoms (LUTSs) which have not been adequately delineated and treated. In young men with LUTS not responding to treatment based on clinical examination, or elderly men with LUTS and incontinence, a complete urodynamic evaluation is mandatory to understand the pathophy...

In this paper we present a chemical and kinematic analysis of two ultra-faint dwarf galaxies (UFDs), Aquarius II (Aqu~II) \text{Bo\"{o}tes II} (Boo~II), using Magellan/IMACS spectroscopy. We the largest sample member stars for Boo~II (12), red-giant-branch members with metallicity measurements Aqu~II (8). both UFDs, over 80\% targets selected based on $Gaia$ proper motions turned out to be spec...

Epigenetics is a burgeoning field of research and many organisms are found to regulate genes in a transient (“above genetics”) way due to (temporarily) decorating DNA or proteins that associate with DNA. This can change transcription of affected genes and since such DNA modifications are reversible, the expression potential over time and generations can therefore be extremely variable. This all...

LUTS, lower urinary tract symptoms QoL, quality of life; QoL can be regarded as covering bothersomeness, impact on quality of life, and sexual functioning BPH, benign prostatic hyperplasia; this term is reserved for the characteristic histological changes associated with BPH BPE, benign prostatic enlargement; this term refers to documented enlargement of the gland BPO, benign prostatic obstruct...

AIMS Intravesical prostatic protrusion (IPP) may be an underutilized modality for the assessment of bladder outlet obstruction (BOO). Pressure flow studies or urodynamics have long been the gold standard for the evaluation of lower urinary tract symptoms (LUTS) in men but are invasive, time-consuming and costly. Potentially, IPP may be a useful adjunct prior to performing urodynamics. METHODS...

INTRODUCTION Prostatectomy for benign disease, also known as a 'simple prostatectomy', is neither simple in indication nor approach. In the post-Medical Therapy of Prostatic Symptoms (MTOPS), NCT00021814 trial era, the medical management of benign prostatic hyperplasia (BPH) and consequent bladder outlet obstruction (BOO) has shifted surgical intervention to those patients who are medical-non r...