Boundary element method (BEM) is one of the numerical methods to solve boundary value problems of partial differential equations. The BEM is especially useful for wave scattering problems for unbounded domains since the numerical solution obtained by BEM automatically satisfies radiation condition, and also, discretisations only of the boundaries are required and those of the domain extending i...

Immobilization devices can impact not only the inter- and intra-fraction motion of the patient, but also the range uncertainty of the treatment beam in proton therapy. In order to limit additional range uncertainty, the water equivalent thickness (WET) of the immobilization device needs to be well known and accurately reflected in the calculations by the treatment planning system (TPS). The met...

the isogeometric analysis is increasingly used in various engineering problems. it is based on non-uniform rational b-splines (nurbs) basis function applied for the solution field approximation and the geometry description. one of the major concerns with this method is finding an efficient approach to impose essential boundary conditions, especially for inhomogeneous boundaries. the main contri...

Sperm immobilization prior to intracytoplasmic sperm injection (ICSI) is thought to be necessary for efficient fertilization. A variety of methods of sperm immobilization (pipetting, squeezing and piezo application) are currently employed in ICSI. The effect of differences in immobilization method on the timing of initial Ca(2+) oscillations of oocytes in ICSI was investigated. Motile spermatoz...

Immobilization of a target molecule to a solid support is an indispensable step in phage display library sorting. Here we describe an immobilization method that addresses shortcomings of existing strategies. Our method is based on the use of a polyhistidine-tagged (His-tagged) target molecule and (BT)tris-NTA, a high-affinity capture reagent for His-tags that also contains a biotin moiety. (BT)...

boundary integral equations (bie) are reformulations of boundary value problems for partial differential equations. there is a plethora of research on numerical methods for all types of these equations such as solving by discretization which includes numerical integration. in this paper, the neumann problem is reformulated to a bie, and then moving least squares as a meshless method is describe...

Recent studies with carbamazepine on human serum albumin (HSA) columns have noted an appreciable degree of non-specific binding on supports prepared by the Schiff base immobilization method. This work examines an alternative immobilization method for HSA based on N-hydroxysuccinimide (NHS)-activated silica. This support was prepared by reacting HPLC-grade silica directly with disuccinimidyl car...