INTRODUCTION The Berlin questionnaire (BQ) is a common tool to screen for Obstructive Sleep Apnea (OSA) in the general population, but its application in the clinical sleep setting is still challenging. The aim of this study was to determine the specificity and sensitivity of the BQ compared to the apnea-hypopnea index obtained from polysomnography recordings obtained from a sleep clinic in Ira...

Benzene is metabolized to a number of electrophilic species that are capable of binding to both DNA and proteins. We used adducts of hemoglobin (Hb) and bone marrow proteins to study the disposition of three benzene and metabolites (benzene oxide [BO], 1,2-benzoquinone [1,2-BQ], and 1,4-benzoquinone [1,4-BQ]) in F344 rats and B6C3F1 mice following a single oral dosage of [13C6]benzene and/or [1...

The Lagrangian Particle Dispersion Model (LPDM) in the 594 km × 594 km model domain with the horizontal grid scale of 3 km × 3 km centered at a power plant and the Eulerian Transport Model (ETM) modified from the Asian Dust Aerosol Model 2 (ADAM2) in the domain of 70° LAT × 140° LON with the horizontal grid scale of 27 km × 27 km have been developed. These models have been implemented to simula...

Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are Nd and Gd (promising for 02 search), Ce (2 candidate with one of the highest Q2). The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2 experiments require development of methods for a de...

Malaysia is among the countries with the highest fish consumption in the world and relies on seafood as a main source of animal protein. Thus, the radioactivity in the mostly consumed marine animals such as fishes, crustaceans and molluscs collected from the coastal waters around Peninsular Malaysia has been determined to monitor the level of human exposure by natural radiation via seafood cons...

Endothelin-1 (ET-1) predominates in the endothelin family effectively in vascular tone control, mitogenesis, and neuromodulation. Its receptors are widespread in the central nervous system (CNS) associated with endogenous pain control, suggesting an important role of ET-1 in central pain processing. This study aimed to evaluate the effect of central ET-1 on the development of neuropathic pain b...

This study examined the role of endothelins (ETs) and their receptor subtypes ETAand ETB in the regulation of vascular tone in the in situ perfused rat left adrenal gland. Endothelin-1 (ET-1), which binds both ETA and ETB receptors, decreased adrenal flow rate of the perfusion medium, and its effect was reversed by the ETA antagonist BQ-123 and enhanced by the ETB antagonist BQ-788. ET-3, which...

BACKGROUND & AIMS Endothelins are expressed in many enteric neurons of the gut. Because activation of endothelin ET(A) and ET(B) receptors is known to alter intestinal muscle activity, the effect of ET(A) and ET(B) receptor agonists and antagonists on propulsive peristalsis was examined. METHODS Repetitive peristalsis in fluid-perfused segments of the guinea pig isolated small intestine was e...

The natural radioactivities of five characteristic igneous rocks of the eastern foreland of the Opava Mountains (Eastern Sudetes, Poland), obtained in the laboratory and under in situ conditions, are presented. The activity concentrations of 232Th, 238U, and 40K were measured using an HPGe gamma-ray spectrometry system. The ranges of the activity concentrations of 232Th were 7-71 Bq kg-1 in the...

abstract background: and soils with which it comes in contact. there is dual exposure from radon in water i.e. due toinhalation of the radon released from the water into the ambient air and through ingestion whenwater is used for drinking. as radon contaminated water adversely affects the health, it istherefore fundamental from health and hygiene point of view to measure radium concentrationand...