نتایج جستجو برای: bradyzoite

تعداد نتایج: 163  

2015
Anahi V. Odell Fanny Tran Jenna E. Foderaro Séverine Poupart Ravi Pathak Nicholas J. Westwood Gary E. Ward

Differentiation of the protozoan parasite Toxoplasma gondii into its latent bradyzoite stage is a key event in the parasite's life cycle. Compound 2 is an imidazopyridine that was previously shown to inhibit the parasite lytic cycle, in part through inhibition of parasite cGMP-dependent protein kinase. We show here that Compound 2 can also enhance parasite differentiation, and we use yeast thre...

Journal: :Transboundary and emerging diseases 2013
P García-Lunar L M Ortega-Mora G Schares N S Gollnick P Jacquiet C Grisez F Prevot C F Frey B Gottstein G Alvarez-García

Bovine besnoitiosis is considered an emerging chronic and debilitating disease in Europe. Many infections remain subclinical, and the only sign of disease is the presence of parasitic cysts in the sclera and conjunctiva. Serological tests are useful for detecting asymptomatic cattle/sub-clinical infections for control purposes, as there are no effective drugs or vaccines. For this purpose, diag...

Journal: :Acta Crystallographica Section F Structural Biology and Crystallization Communications 2008

2015
Zi Teng Wang L. David Sibley

In their letter, McConkey et al. (1) suggest that differences in study design may have led to different results in our study compared with those of previous reports. In an effort to better understand these differences, we welcome the opportunity to provide more insight into the rationale for our study design and the reasoning behind the interpretations we reached. We stress at the outset that w...

Journal: :Infection and immunity 2015
Glenn A McConkey Chris Peers Emese Prandovszky

In their letter, McConkey et al. (1) suggest that differences in study design may have led to different results in our study compared with those of previous reports. In an effort to better understand these differences, we welcome the opportunity to provide more insight into the rationale for our study design and the reasoning behind the interpretations we reached. We stress at the outset that w...

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