1. Eindhoven JA, van den Bosch AE, Jansen PR, Boersma E, RoosHesselink JW. The usefulness of brain natriuretic peptide in complex congenital heart disease: a systematic review. J Am Coll Cardiol 2012;60: 2140–9. 2. Johns MC, Stephenson C. Amino-terminal pro-B-type natriuretic peptide testing in neonatal and pediatric patients. Am J Cardiol 2008;101:76–81. 3. Clerico A, Emdin M. Diagnostic accur...

1. Introduction smaller fragments some of which may also have biological activity [5]. Less is known about the procession of BNP; it In the 20 years which have passed since the first is believed to be more constitutively expressed. Pro-brain description by de Bold of a natriuretic and diuretic natriuretic peptide is a 108-amino acid peptide also cleaved substance produced in the heart [1], a la...

Introduction: The aim of this study was to evaluate the effects of aerobic exercise on brain natriuretic peptide (BNP) and C-reactive protein (CRP) levels in women with cardiovascular diseases. Materials and Methods: In this semi experimental study, thirty female patients with at least one coronary artery stenosis (more than70%) were chosen and divided into two groups of aerobic training (n=15)...

Chronic treatment with suprapharmacologic doses of peroxisome proliferator-activated receptor (PPAR) agonists has a known potential for causing left ventricular hypertrophy (LVH). The mechanism by which LVH develops is not well understood nor are biomarkers of it well characterized. Natriuretic peptides are important regulators of cardiac growth, blood volume, and arterial pressure and may be u...

Little information is available about the potential role of brain (type B) natriuretic peptide in patients with acute myocardial infarction. We therefore analyzed peptide levels, measured at discharge from our coronary care unit, in 56 patients admitted with a diagnosis of acute myocardial infarction. We examined peptide concentrations in the light of different features in our patients, and fou...

OBJECTIVE To demonstrate the presence and importance of apoptotic activity in heart failure during acute exacerbations and to investigate the effects of different drugs used and co-morbidities on levels of N-Terminal pro-Brain Natriuretic Peptide and apoptotic activity on admission and during hospitalisation. METHODS The descriptive study was conducted at the emergency department of Istanbul ...

Background Hypertension is the second most common cause of maternal death in world. Predicting occurrence preeclampsia (PE) complications needed to optimize management. Brain natriuretic peptide (BNP) a polypeptide, secreted by cardiac ventricular myocytes. Research linking N-Terminal Pro B-Type Natriuretic Peptide (NT-proBNP) levels with has never been conducted Indonesia. The aim study evalua...

In 1988 Sudoh and colleagues described a novel natriuretic peptide in porcine brain -brain natriuretic peptide(Sudoh et al. 1988). In fact, the peptide is most abundant in the heart and thus it is now commonly termed B-type natriuretic peptide (BNP). Myocyte pressure and/or stretch results in the release of BNP, and BNP levels are easily quantified by several commercially available assays. Data...

UNLABELLED In 1,049 patients with stable ischemic heart disease (IHD), brain natriuretic peptide (BNP) and amino terminal pro-brain natriuretic peptide (NTproBNP) correlated closely (r = 0.09, p < 0.001) and were similarly related to left ventricular ejection fraction (LVEF) (r = -0.50 and -0.46, respectively), age (0.44 and 0.47), and creatinine clearance (-0.51 and -0.51). Receiver-operating ...