Abstract Background Cavernous sinus syndrome (CSS) consists of a variable combination involvement the 3rd-to-6th cranial nerves. The etiologies vary across studies, and it has significant impact on outcome. This study was done to delineate etiology, clinico-radiological profile outcome CSS. In this prospective study, patients were recruited consecutively over 2 years, followed up for at least 6...

The heart and the brain had for thousands of years been considered the "noble" organs, organs shrouded in the deepest of mysteries, highly organized masses of tissues properly hidden from man's prying eyes and curious fingers. They were not to be touched under any circumstances ; they held the secrets of life and death and for that reason were sacred in the sight of God. So it was that for two ...

Both brain injury and tacrolimus have been reported to promote the regeneration of injured peripheral nerves. In this study, before transection of rat sciatic nerve, moderate brain contusion was (or was not) induced. After sciatic nerve injury, tacrolimus, an immunosuppressant, was (or was not) intraperitoneally administered. At 4, 8 and 12 weeks after surgery, Masson's trichrome, hematoxylin-e...

OBJECTIVE The aim of this study was to evaluate the microanatomy and histological features of the central myelin in the root exit zone of facial nerve. METHODS Forty facial nerves with brain stem were obtained from 20 formalin fixed cadavers. Among them 17 facial nerves were ruined during preparation and 23 root entry zone (REZ) of facial nerves could be examined. The length of medial REZ, fr...

objective(s) achillea genius is widely used in traditional medicine for gastrointestinal disorders. the aim of this study was to investigate the effects of aqueous-ethanol extract of achillea wilhelmsii on rat’s gastric motility in basal and vagal stimulated conditions. materials and methods twenty four wistar rats were randomly divided into two groups: control and test. the extract was prepare...

Brain perfusion is tightly coupled to neuronal activity, is commonly used to monitor normal or pathological brain function, and is a direct reflection of the interactions that occur between neuronal signals and blood vessels. Cerebral blood vessels at the surface and within the brain are surrounded by nerve fibers that originate, respectively, from peripheral nerve ganglia and intrinsic brain n...

When the organ systems of the body are studied from an engineering point of view, electricity emerges as the essence of human life. In fact, life itself is now taken to exist only so long as the brain produces measurable electrical activity. It is not surprising, then, that medical practitioners have been fascinated by the effects of externally applied electricity since the beginning of medicin...

The cytokine IL-6, which is released upon peripheral immune challenge, is critical for the febrile response, but the mechanism by which IL-6 is pyrogenic has remained obscure. Here we generated mice with deletion of the membrane bound IL-6 receptor α (IL-6Rα) on neural cells, on peripheral nerves, on fine sensory afferent fibers, and on brain endothelial cells, respectively, and examined its ro...

GBS and its MFS variant are acute polyneuropathies that are considered to represent a continuum rather than distinct entities, due to the overlap in their clinical features. Enhancement of the CE roots represents the neuroradiologic hallmark of GBS, while findings of neuroimaging studies in MFS are usually unremarkable. Our purpose was to evaluate the MR imaging findings of polyneuropathy in 17...

Opportunities and Prospects Authors: V. Pokrovskii Affiliations: Kuban State Medical University, Department of Normal Physiology, Sedin Street, 4, 350063, Krasnodar, Russia, [email protected] , http://www.pokrovskii.kuban.ru. Abstract: In this article the example of the mechanisms of heart rhythmogenesis in the intact organism to demonstrate the new capabilities provided by an integrative a...