To determine whether an automated extraction of the brain-tissue region from CT images is useful for the histogram analysis of the brain-tissue region was studied. We used the CT images of 11 patients. We developed an automatic brain-tissue extraction algorithm. We evaluated the similarity index of this automated extraction method relative to manual extraction, and we compared the mean CT numbe...

Many hereditary diseases are characterized by region-specific toxicity, despite the fact that disease-linked proteins are generally ubiquitously expressed. The underlying basis of the region-specific vulnerability remains enigmatic. Here, we evaluate the fundamental features of mitochondrial and glucose metabolism in synaptosomes from four brain regions in basal and stressed states. Although th...

Despite the emerging applications of diffusion tensor imaging (DTI) [1,4], there is a lack of longitudinal investigation on the evolution of diffusion based patterns in mild traumatic brain injury (mTBI), which may help to predict the recovery and assist in studying the long term impact caused by mTBI. Although the newly developed DTI techniques, such as voxel-wise analysis, region of interest ...

background: alzheimer's disease is the most common form of dementia which is still difficult to be differentiated from other types of brain disorders. moreover, mild cognitive impairment refers to the presence of cognitive impairments that is not severe enough to meet the criteria of alzheimer's, and its diagnosis in early stages is so critical. there is currently no distinct method available f...

miconazole is an imidazole antifungal agent, commonly applied topically to the skin or mucous membranes. the aim of this study was to examine the alternative method for gaining mechanism or the bimolecular changes caused by the possible teratogenic effects of miconazole on mice fetus brain tissue using ftir-microspectroscopy. the mice were injected with miconazole (60 mg/kg) on gestation day 9....

Introduction: Orthogonal radial fields are those in which the central axes are perpendicular to each other. An example of these orthogonal fields is the set of craniospinal orthogonal fields that are used for radiotherapy of medulloblastoma. Craniospinal radial fields consist of two parallel-opposed fields for brain exposure and one or two posterior spinal fields for spinal cord exposure. The m...

Besides the classical form of bovine spongiform encephalopathy (BSE) that has been known for almost three decades, two atypical forms designated H-type and L-type BSE have recently been described. While the main diagnostic feature of these forms is the altered biochemical profile of the accumulated PrP(Sc), it was also observed in the initial analysis that L-type BSE displays a distribution pat...

Hemangioblastoma (HB) in the supratentorial region of the brain is rare and only a few cases are reported on intraventricular HB. HB of the lateral ventricles is even rarer. We present a case of a 30-year-old man with generalized tonic clonic seizures. The brain computed tomography showed a 5.5 cm heterogeneous mass extending into both lateral ventricles with partial enhancement. Based on the s...

Introduction: Autism is a heterogeneous neurodevelopmental disorder associated with social, cognitive and behavioral impairments. These impairments are often reported along with alteration of the brain structure such as abnormal changes in the grey matter (GM) density. However, it is not yet clear whether these changes could be used to differentiate various subtypes of autism spectrum disorder ...

introduction: orthogonal radial fields are those in which the central axes are perpendicular to each other. an example of these orthogonal fields is the set of craniospinal orthogonal fields that are used for radiotherapy of medulloblastoma. craniospinal radial fields consist of two parallel-opposed fields for brain exposure and one or two posterior spinal fields for spinal cord exposure. the m...