INTRODUCTION We believe that conservative treatment of early breast cancer may not require radiotherapy that encompasses the whole breast. We present here the clinico-pathological basis for this view, as well as a novel therapeutic approach that allows intra-operative radiotherapy to be safely and accurately delivered to the target tissues in a standard operating theatre. THE RATIONALE: Whole-o...

PURPOSE The purpose of this study was to compare the surface dose of 7-field IMRT (7 F-IMRT), tangential beam IMRT (TB-IMRT), and tangential beam 3D-CRT (3D-CRT) of breast cancer patients receiving adjuvant radiotherapy by means of in vivo GafChromic film dosimetry. MATERIAL AND METHODS Breast cancer patients receiving adjuvant radiotherapy of the whole breast or the chest wall were eligible ...

AIMS AND BACKGROUND To investigate the impact of postchemotherapy mammography on radiotherapy timing and detection of early locoregional recurrences in breast cancer patients treated with breast-conserving surgery and adjuvant chemotherapy. METHODS Bilateral mammography was performed before radiotherapy. Mammogram assessments were collected using the Breast Imaging Reporting and Data System (...

BACKGROUND The authors performed a systematic review of the literature on the outcome of therapy for patients with breast cancer who underwent adjuvant radiotherapy after an immediate two-stage prosthetic breast reconstruction, either following tissue expansion (stage 1) or after removal of the tissue expander and insertion of a final breast implant (stage 2). Their outcomes were compared to th...

Breast-conserving surgery including whole breast irradiation has long been a recommended procedure for early breast cancer. However, conventionally fractionated radiotherapy requires a lengthy hospitalisation or prolonged commuting to a hospital for radiotherapy. In recent years, hypofractionated radiotherapy has increasingly been used. This method involves higher fraction doses (above 2 Gy) as...

BACKGROUND AND PURPOSE We report a systematic review of lung radiation doses from breast cancer radiotherapy. METHODS AND MATERIALS Studies describing breast cancer radiotherapy regimens published during 2010-2015 and reporting lung dose were included. Doses were compared between different countries, anatomical regions irradiated, techniques and use of breathing adaptation. RESULTS 471 regi...

Breast cancer is the most common cancer in women of developed countries. Early stage diagnosis is followed, in many cases, of conservative surgery and local radiotherapy. This treatment reduces loco-regional recurrences but may be accompanied by local complications. Morphea of the breast is an uncommon skin condition and has been described after radiotherapy. The inflammatory stage of morphea c...

ABSTRACT Objective: To estimate the incidence and degree of acute radiodermatitis at end after treatment in women with breast cancer undergoing hypofractionated radiotherapy. Methods: Observational, prospective, longitudinal study, conducted between March 2019 January 2020, a radiotherapy outpatient clinic. Results: Thirty-two participated among whom, last session radiotherapy, 15 (46.9%) had r...

Despite wide efforts for early detection of breast cancer using screening mammography, locally advanced breast carcinomas account for a remarkable proportion of all breast carcinomas, particularly in developing countries. Locally advanced breast cancer may have widely different clinical and biological features. Radiotherapy plays an important role in the management of locally advanced breast ca...

Whole breast external beam radiotherapy is an effective adjuvant treatment for early breast cancer, and was a key factor in the move from mastectomy to breast-conserving surgery for women with low-risk disease. The logical development from partial surgical removal of the breast is partial breast radiotherapy. Several methods of delivery have been investigated, but as yet none has been widely ac...