Growing evidence suggests that on-pathway amyloid-β (Aβ) oligomers are primary neurotoxic species and have a direct correlation with the onset of Alzheimer's disease (AD). One promising therapeutic strategy to block AD progression is to reduce the levels of these neurotoxic Aβ species using small molecules. While several compounds have been shown to modulate Aβ aggregation, compounds with such ...

We have evaluated urinary monitoring and erythrocyte analysis to determine Mg absorption in human subjects as alternatives to the conventional technique of faecal monitoring by stable-isotope techniques. Ten healthy adults received 2.2 mmol (25)Mg in water, together with wheat bread, followed 15 min later by intravenous injection of 0.6 mmol (26)Mg (day 1). Brilliant blue and Yb (given on day 0...

In many industrial areas such as in food, pharmaceutical, cosmetic, printing, and textile, the use of synthetic dyes has been integral with products such as azo dye, anthrax, and dyestuffs. As such, these industries produce a lot of waste by-products that could contaminate the environment. Bioremediation, therefore, has become an important emerging technology due to its cost-sustainable, effect...

Insoluble Dendronized Chitosan (DCTS) was prepared to improve the adsorption capacity of chitosan (CTS) as well as to lower its solubility at lower pH for efficient removal of acid dye, Acid Blue 9 (AB 9) from aqueous solutions. Dendronized chitosan was prepared by grafting ‘dendrimer-like’ Polyamidoamine (PAMAM) onto CTS surface using Michael addition reaction followed by amidation reaction. T...

Conventional light microscopy techniques are poorly suited for imaging the vertical cell dimension. This can be accomplished using transmission-through-dye (TTD) imaging, in which cell thickness is directly converted into image intensity in the presence of extracellular dye with strong absorption. We have previously described applications of TTD to living cells using the dye Acid Blue 9 (AB9) t...

This study is focused on development of a method of TiO2 immobilization, convenient for the wastewater remediation (especially for the degradation of textile dyes) and cheap for an industrial operation. An influence of selected operational parameters on process performance was verified. Methylene Blue was chosen as the model dye, however, a possibility of decolorization of other dyes was also t...

Biological hydrogels consisting of self-assembling peptide nanofibers are potentially excellent materials for various controlled molecular release applications. The individual nanofiber consists of ionic self-complementary peptides with 16 amino acids (RADA16, Ac-RADARADARADARADA-CONH(2)) that are characterized by a stable beta-sheet structure and undergo self-assembly into hydrogels containing...

This work studied the potential use of horseradish peroxidase (HRP) in the decolorization of the following textile dyes: Drimarene Blue X-3LR (DMBLR), Drimarene Blue X-BLN (DMBBLN), Drimarene Rubinol X-3LR (DMR), and Drimarene Blue CL-R (RBBR). Dyes were individually tested in the reaction media containing 120 mg·L(-1), considering the following parameters: temperature (20-45°C), H(2)O(2) conce...

BACKGROUND Studies were carried on the decolorization of the textile dye reactive blue 19 (RB 19) by a novel isolate of Coprinus plicatilis (C. plicatilis) fungi. We describe an in vitro optimization process for decolorization and its behavior under different conditions of carbon and nitrogen sources, pH, temperature and substrate concentration. RESULTS The optimal conditions for decolorizati...

In the present study, a crude laccase preparation from Pleurotus ostreatus was successfully immobilized on perlite, a cheap porous silica material, and tested for Remazol Brilliant Blue R (RBBR) decolourisation in a fluidized bed recycle reactor. Results showed that RBBR decolourisation is mainly due to enzyme action despite the occurrence of dye adsorption-related enzyme inhibition. Fine tunin...