A patient is reported who presented with features of bronchial obstruction due to endobronchial tumour. Failure to recognise this as being due to choriocarcinoma led to a delay in diagnosis and effective treatment which, given earlier, may have proved lifesaving.

Asthma is defined as a disease of the respiratory passages characterized by dyspnoea of an obstructive type which is predominantly expiratory, reversible at least partially, and of varying severity and duration (Meneely et al., 1962). The anatomical and biochemical basis of the bronchial obstruction has been reviewed by Middleton (1959). In the present review emphasis is put on the allergic asp...

BACKGROUND Asthma and excessive body weight frequently coexist, whereas the exact relationship between the 2 diseases is unknown. OBJECTIVE To study whether asthma combined with excessive body weight has a greater effect on quality of life in children than the separate effects of asthma or excessive body weight alone. METHODS In a cross-sectional design, 1758 school children (age 7-10 years...

The significance of severe airflow obstruction in severe asthma is unclear. The current study determined whether severe airflow obstruction is related to inflammatory or structural changes in the airways. Patients with severe asthma from a tertiary referral clinic were divided into two groups according to their postbronchodilator forced expiratory volume in one second (FEV1): severe persistent ...

The relation between citric acid cough threshold and airway hyperresponsiveness was investigated in 11 non-smoking patients with allergic asthma (mean FEV1 94% predicted) and 25 non-atopic smokers with chronic airflow obstruction (mean FEV1 65% predicted). Cough threshold was determined on two occasions by administering doubling concentrations of citric acid. Seven of the 11 asthmatic subjects ...

Two cases of congenital bronchial atresia with pectus excavatum are reported. Costosternal retraction during the efforts to overcome the airway obstruction due to encroachment on normal lung tissue by the hyperinflated segments may play a part in causing pectus excavatum.

A case of localized tracheobronchial primary amyloidosis masquerading as "bronchial asthma" is presented. Computed tomography of the chest and fiberoptic bronchoscopy image are included. Tracheobronchial primary amyloidosis is a rare, but potentially curable cause of airway obstruction mimicking asthma.

BACKGROUND Obstructive airways disease adversely affects quality of life, although relationships between quality of life and lung function have been shown to be weak. The relationships between the results of a quality of life questionnaire, spirometric tests, and methacholine bronchial challenge were investigated in a population sample of middle aged and elderly people. METHODS A random popul...

To date, methods of studying the effects drugs at molecular-genetic level are widely used in pediatric practice. The aim our work was to evaluate effectiveness effect β2-agonists on clinical course recurrent bronchial obstruction (RBO) children, depending variants polymorphism ADRB2 gene. salbutamol children with RBO and asthma(BA) evaluated distribution alleles genotypes Argl6Gly Gln27Glu gene...