The frequent dispensability of duplicated genes in budding yeast is heralded as a hallmark of genetic robustness contributed by genetic redundancy. However, theoretical predictions suggest such backup by redundancy is evolutionarily unstable, and the extent of genetic robustness contributed from redundancy remains controversial. It is anticipated that, to achieve mutual buffering, the duplicate...

Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org/page/info/about/policies/terms.jsp. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive o...

Dopamine (DA)-containing cells from the substantia nigra pars compacta (SNc) play a major role in the initiation of movement. Loss of these cells results in Parkinson's disease (PD). Changes in intracellular calcium ion concentration ([Ca(2+)](i)) elicit several events in DA cells, including spike afterhyperpolarizations (AHPs) and subthreshold oscillations underlying autonomous firing. Continu...

42 43 Dopamine (DA) containing cells from the substantia nigra pars compacta (SNc) play a 44 major role in the initiation of movement. Loss of these cells results in Parkinson’s 45 disease (PD). Changes in [Ca]i elicit several events in DA cells, including spike 46 afterhyperpolarizations (AHPs) and subthreshold oscillations underlying autonomous 47 firing. Continuous Ca load due to Ca-dependen...

AIM The aim of this report is to describe the relationship of some salivary parameters to dental erosion resulting from excessive citric acid consumption and present a description of a prosthetic approach used to restore the damaged dentition of a patient with severe erosion. BACKGROUND The high consumption of dietary sources of acids can lead to erosion or the excessive wear of dental hard t...

The arterial baroreflex buffers slow (<0.05 Hz) blood pressure (BP) fluctuations, mainly by controlling peripheral resistance. Baroreflex sensitivity (BRS), an important characteristic of baroreflex control, is often noninvasively assessed by relating heart rate (HR) fluctuations to BP fluctuations; more specifically, spectral BRS assessment techniques focus on the BP-to-HR transfer function ar...

PURPOSE To investigate the buffering capacity of restorative materials during a simulated carious and intrinsic erosive attack. MATERIALS AND METHODS Cavities with a volume of 130 μl were milled (Cerec MC XL) out of blocks of Ceram X Mono (CM), Quixfil (QX), Filtek Supreme (FS), Apa Fill 3 (AF), an experimental dual-curing composite containing a bioactive glass (EX), Dyract eXtra (DY), Beauti...

The structural, chemical and electronic changes of ceria as a function of decreasing particle size have been studied: at sizes below 5 nm the total amount of reducible oxygen dramatically increases due to superoxide formation on the ceria surface, a result indicative of a size dependent oxygen buffering capacity.

Video streaming is in high demand by mobile users, as recent studies indicate. In cellular networks, however, the unreliable wireless channel leads to two major problems. Poor channel states degrade video quality and interrupt the playback when a user cannot sufficiently fill its local playout buffer: buffer underruns occur. In contrast to that, good channel conditions cause common greedy buffe...

BACKGROUND The aim of the study was to assess the oral health status and treatment needs and correlation between dental caries susceptibility and salivary pH, buffering capacity and total antioxidant capacity among students attending special schools of Mangalore city. MATERIALS AND METHODS In this study 361 subjects in the age range of 12-18 years were divided into normal (n = 84), physically...