BACKGROUND Crocodile oil and its products are used as ointments for burns and scalds in traditional medicines. A new ointment formulation - crocodile oil burn ointment (COBO) was developed to provide more efficient wound healing activity. The purpose of the study was to evaluate the burn healing efficacy of this new formulation by employing deep second-degree burns in a Wistar rat model. The an...

Background and objectives: Severe burn damage and its consequences are life threatening which can complicate patients’ health. Burn damage increases reactive oxygen species (ROS) generation which leads to severe damage to tissues and is implicated in burn shock. Some medicinal and traditional plants are considered as safe, natural and inexpensive sources for treatment of differ...

materials and methods in this study, 90 patients with second-degree burn injuries who were admitted to the yazd burn hospital were randomly divided into three equal groups. in the negative control group, the wounds were covered with sterile vaseline gauze followed by double sterile dry gauze and ultimately bandaged. in the test group, the wounds were covered by an iranian hydrogel sheet (irgel)...

Accelerating the healing process and reducing pain during healing are beneficial for the following reasons: faster return to work, lower risk of wound infection, improved quality of life, and possibly reduced need for analgesia. This clinical study assessed the effectiveness of a new oxygen-diffusion dressing (OxyBand; Oxyband Technologies, St. Louis, MO) compared with standard Xeroform gauze d...

OBJECTIVES The study was undertaken to evaluate the burn wound healing property of oil of Cocos nucifera and to compare the effect of the combination of oil of Cocos nucifera and silver sulphadiazine with silver sulphadiazine alone. MATERIALS AND METHODS Partial thickness burn wounds were inflicted upon four groups of six rats each. Group I was assigned as control, Group II received the stand...

We report on the use of a high-speed, fiber-based Mueller-matrix optical coherence tomography system with continuous source-polarization modulation for in vivo burn depth evaluation and healing monitoring. A homemade hand-held probe with integrated optical scanning and beam delivering optics was coupled in the sample arm. In vivo burn imaging was demonstrated on porcine skin at different stages...

BACKGROUND This experiment was performed to compare the effects of Phenytoin (PHT) and Hypericin (HP) cream on healing of burn wounds in rats. MATERIAL AND METHODS Twenty rats were divided into 3 groups and second-degree burn wounds were created. The burn wounds in the first, second, and third groups were covered twice daily with PHT cream, HP cream, and saline (control), respectively. At the...

BACKGROUND In the context of the search for cost-efficient treatments, Ulmo (Eurcyphia cordifolia) honey is an excellent alternative for treating burn wounds and could have a profound medical, social, and economic impact. Ascorbic acid is an enzymatic co-factor necessary for the synthesis of collagen and the proliferation of fibroblasts and has been proposed as a coadjuvant to strengthen the he...

Background: Efficacy of Centella asiatica on incision and burn wounds are not sufficiently known. In this study we evaluated[SYG1] wound healing activities of different extracts of Centella asiatica, namely hexane, ethyl acetate, methanol, and water extracts, in incision and partial-thickness burn wound models in rats. Results: On day 7 post-wounding, tensile strength of incision wound in all e...