The elucidation of pathways linking patterning to morphogenesis is a problem of great interest. We show here that, in addition to their roles in patterning and morphogenesis of the hindgut, the Drosophila genes drumstick (drm) and bowl are required in the foregut for spatially localized gene expression and the morphogenetic processes that form the proventriculus. drm and bowl belong to a family...

Methylarachidonylfluorophosphonate (MAFP) and related analogs have been shown to inhibit fatty acid amidohydrolase activity (FAAH), the enzyme responsible for hydrolysis of the endogenous cannabinoid ligand anandamide. To fully characterize this class of compounds, methylfluorophosphonate compounds with saturated alkyl chains ranging from C8 to C20 along with C20 unsaturated derivatives were sy...

A survey given to animal shelters across the US reported food bowl guarding as one of the most common reasons for euthanasia and only 34% attempted to modify this guarding behavior. This study identified 96 dogs that guarded their food bowl during an assessment, and then placed them into a home on a modification program. Food guarding behavior was identified as stiffening, gulping, growling, fr...

The bowl-championship-series (BCS) committee uses 10 ranking schemes, including eight computer rankings, to select college football teams for bowl-championship-series bowl games, including the national championship game. The large financial benefits of participating in BCS bowl games make it imperative that the selection process accurately select the best teams. I evaluated the performance of t...

BACKGROUND Numerous cartilage grafts from a number of donor sites have been described, each with a different shape and size. These donor sites include the nasal septum, costal chondral cartilage, and the conchal bowl. Although harvests from the conchal bowl are commonly-employed, the techniques have been minimally-described in the literature, particularly as it applies to rhinoplasty. OBJECTI...