Viruses in the rhinovirus C species (RV-C) can cause severe respiratory illnesses in children including pneumonia and asthma exacerbations. A transduced cell line (HeLa-E8) stably expressing the CDHR3-Y529 receptor variant, supports propagation of RV-C after infection. C15 clinical or recombinant isolates replicate in HeLa-E8, however progeny yields are lower than those of related strains of RV...

In all organisms, translational initiation takes place on the small ribosomal subunit and two classes of methionine tRNA are present. The initiator is used exclusively for initiation of protein synthesis while the elongator is used for inserting methionine internally in the nascent polypeptide chain. The crystal structure of Escherichia coli initiator tRNA(f)(Met) has been solved at 3.1 A resol...

In this paper, we propose a class of ACD-type models that accommodates overdispersion, intermittent dynamics, multiple regimes, and sign and size asymmetries in financial durations. In particular, our functional coefficient autoregressive conditional duration (FC-ACD) model relies on a smooth-transition autoregressive specification. The motivation lies on the fact that the latter yields a unive...

Am I Missing Something? The Effects of Absence from Class on Student Performance We exploit a rich administrative panel data-set for cohorts of Economics students at a UK university in order to identify causal effects of class absence on student performance. We utilise the panel properties of the data to control for unobserved heterogeneity across students and hence for endogeneity between abse...

The recent availability of large data sets covering single transactions on nancial markets has created a new branch of econometrics which has opened up a new door of looking at the microstructure of nancial markets and its dynamics. The speci c nature of transaction data such as the randomness of arrival times of trades, the discreteness of price jumps and signi cant intraday seasonalities, cal...

We estimate a spatially explicit model of the forest clearance process among smallholder farmers in an agricultural frontier of southern Mexico. Our analysis takes as its point of departure a simple utility-maximising model that suggests many possible determinants of deforestation in an economic environment characterised by missing or thin markets. Hypotheses from the model are tested on a data...

This paper generalizes existing econometric models for censored competing risks by introducing a new flexible specification based on a piecewise linear baseline hazard, time-varying regressors, and unobserved individual heterogeneity distributed as an infinite mixture of Generalized Inverse Gaussian (GIG) densities, nesting the gamma kernel as a special case. A common correlated latent time eff...

Two measures of unemployment duration were obtained for each individual from data collected by Istat through the Quarterly Labour Force Survey. One measure was the length of on-going spells of unemployment, declared by the interviewed individual in a first wave and suitably adjusted considering information in a second wave (Spell Answers). The other was the time elapsed between the dates of the...

This paper proposes to model movements in more than a century of daily US stock prices as the outcome of a multi-state marked point process and studies the time it takes for stock prices to complete an up or a down move of a certain size. We present a new econometric specification for a class of dynamic models that account for autoregressive conditional duration effects. We also present a metho...