objective: considering the use of triple antibiotic paste (tap) for root canal treatment of open apex teeth, this study aimed to assess the effect of tap and calcium hydroxide (ch) on bond strength of composite to dentin.   methods: this in-vitro study was conducted on 32 extracted human premolar teeth. after disinfection with 2% thymol solution, the enamel on the buccal surface of specimens wa...

The present study was conducted to determine the influence of 2 intracanal medicaments (calcium hydroxide, chlorhexidine gel 2%) when used either alone or combined on the short- and long-term sealing ability of permanent root canal fillings. Ninety human upper central incisors were divided into 4 experimental groups (n=20). All root canals were instrumented in a step-back motion and then treate...

There is overwhelming evidence that endodontic diseases can be characterized as infectious diseases. There is no longer any question that microorganisms are at the center of the etiological causes of pulpal and periradicular pathological processes (1, 2). There are many secondary reasons contributing to tissue breakdown and endodontic failures, such as root perforations, instrument fractures, e...

During clinical endodontic treatment, we often find radiopaque filling material beyond the root apex. Accidental extrusion of calcium hydroxide could cause the injury of inferior alveolar nerve, such as paresthesia or continuous inflammatory response. This case report presents the extrusion of calcium hydroxide and treatment procedures including surgical intervention. A 48 yr old female patient...

INTRODUCTION Irrigants play an essential role in the successful debridement and disinfection of pulp space. Various combination of irrigants used during root canal treatment enhance their efficacy, but some form precipitates which affects the diffusion of intracanal medicaments and the seal of the obturated root canal. AIM To evaluate the combination of various irrigants whether it forms the ...

Inflammatory external root resorption (IERR) is a pathological phenomenon of microbial origin. This study reports a case of external apical inflammatory root resorption of maxillary incisors associated with periradicular lesions in a 22 year old female, which was successfully treated by one-visit root canal therapy (RCT). Radiographic investigation revealed periapical radiolucencies in the uppe...

AIM The focus of this study was to examine the staining potential of calcium hydroxide (Ca(OH)2) on tooth structure following the removal of AH26 root canal sealer. METHODS AND MATERIALS Fifty maxillary anterior teeth were prepared and obturated with AH26 and gutta percha. The sealers were then removed 24 hours later and the teeth were randomly divided into two groups. Ca(OH)2 was then placed...

Apart from isolated reports of severe salicylate poisoning after ingesting an unusually large amount of a medicinal oil, there are no published data on the threat arising from attempted suicide with topical medicaments containing methyl salicylate or wintergreen oil compared with aspirin tablets. In this retrospective study, the admission plasma salicylate concentrations and clinical presentati...

The antibacterial activity of β-lactam derived polycyclic fused pyrrolidine/pyrrolizidine derivatives synthesized by 1, 3-dipolar cycloaddition reaction was evaluated against microbes involved in dental infection. Fifteen compounds were screened; among them compound 3 showed efficient antibacterial activity in an ex vivo dentinal tubule model and in vivo mice infectious model. In silico docking...

Background: A successful endodontic treatment is inseparable from the right choice of root canal dressing. The medicaments would result in patient satisfaction. Enterococcus faecalis (E. faecalis) and Porphyromonas gingivalis (P. gingivalis) are usually found failed treatments. Calcium hydroxide a gold standard dressing that creates an alkaline environment has bactericidal effect. Commercially,...