deproteinisation with acetonitrile (along with methanol or other reagents) is a useful and rapid technique in analysis of drugs or their metabolites in human serum. in this paper application of this simple technique in biopharmaceutical analysis using capillary electrophoresis (ce) is evaluated. some drugs with different ionic and protein binding properties were selected and dissolved in human ...

Capillary electrophoresis (CE) with indirect UV detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. Good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in CE. It is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...

An arteriovenous malformation is an anomaly of capillary development that results in a direct connection between branches of an artery and veins, with no intervening capillary network. Vascular malformations of the mediastinum presenting as mediastinal masses are very rare. We report a histologically proven case of a posterior mediastinal arteriovenous malformation in a 42-year-old man that was...

els has proved to be a useful method for the study of the capillary circulation of the lung. Until recenth’, we felt that studying the capillary circulation in the component parts of the primary lobule** would reveal all the aspects of the terminal arterial circulation. It has been found, however, that the primary lobule does not disclose all the details of the terminal arterial vessels and the...

PURPOSE We investigated quantitatively the distribution of blood vessels in different neural layers of the human retina. METHODS A total of 16 human donor eyes was perfusion-fixed and labeled for endothelial f-actin. Retinal eccentricity located 3 mm superior to the optic disk was studied using confocal scanning laser microscopy. Immunohistochemical methods applied to whole-mount and transver...