A slightly deformable network may be considered as a particular porous media with a connected void phase. In this paper, a fluid flow through a collagen network is analyzed with applications in the area of restorative dentistry. Infiltration of a fluid into a network already saturated by another fluid is a complex issue especially when the fibers are so tightly distributed (10 to 100 nm between...

A miniaturized pepsin reactor was prepared inside a fused-silica capillary (i.d. 75 microm) by coating a pepsin-containing gel on a photopolymerized porous silica monolith. The pepsin-encapsulated film was prepared by a sol-gel method. The sol-gel reaction was optimized so that the sol solution containing pepsin forms a thin film on the photopolymerized sol-gel (PSG) monolith that was initially...

A rapid and sensitive immunoassay platform integrating polymerized monoliths and gold nanoparticles (AuNPs) has been developed. The porous monoliths are photopolymerized in situ within a silica capillary and serve as solid support for high-mass transport and high-density capture antibody immobilization to create a shorter diffusion length for antibody-antigen interactions, resulting in a rapid ...

We investigate the phase diagram of a two-component associating fluid mixture in the presence of selectively adsorbing substrates. The mixture is characterized by a bulk phase diagram that displays peculiar features such as closed loops of immiscibility. The presence of the substrates may interfere with the physical mechanism involved in the appearance of these phase diagrams, leading to an enh...

Effects of the bounding solid walls are examined numerically for slow flow over regular, square arrays of circular cylinders between two parallel plates. A local magnitude of the rate of entropy generation is used effectively to determine the flow region affected by the presence of the solid boundary. Computed axial pressure gradients are compared to the corresponding solution based on the Darc...

Computational pore-scale network models describe two-phase porous media ̄ow systems by resolving individual interfaces at the pore scale, and tracking these interfaces through the pore network. Coupled with volume averaging techniques, these models can reproduce relationships between measured variables like capillary pressure, saturation, and relative permeability. In addition, these models all...