goes a profound change in electronic structure on attachment to hemoglobin. The magnetic susceptibility of hemoglobin itself (ferrohemoglobin) corresponds to an effective magnetic moment of 5.46 Bohr magnetons per heme, calculated for independent hemes. This shows the presence of four unpaired electrons per heme, and indicates that the heme-heme interaction tends to stabilize to some extent the...

Carboxyhaemoglobin concentrations (COHb) have been measured in groups of individuals smoking while engaged in different activities. The three groups chosen (meat porters, office workers, and pregnant women) had finger-prick blood samples taken at about six hours into their working day. COHb was measured by the method of Commins and Lawther (1965), a method subsequently shown to have a mean erro...

A combined stopped flow-laser photolysis apparatus was used to measure the quantum efficiency for removal of carbon monoxide bound to human hemoglobin as a function of fractional CO saturation. This flow-flash technique allows the properties of partially liganded hemoglobin molecules, which are sparsely populated under equilibrium conditions, to be conveniently studied. Experiments performed at...

The gaschromatographic determination of CO in blood has been simplified by using carbon molecular sieve columns for separation of gases. Regeneration of the columns is necessary only after 1000 and more analyses. Moreover, a more simple procedure for evaluating the CO concentration was developed. This procedure is suitable for routine determination in the sensitivity range of 0.2—100 % COHb in ...

Objectives At the completion of this course, the learner should be able to: 1. Describe a waterpipe (hookah) that is used to smoke tobacco. 2. Discuss the toxicants in waterpipe smoke. 3. Discuss the toxicants that can be found in waterpipe smokers. 4. Identify 3 potential health risks of waterpipe tobacco smoking. 5. Describe why a preoperative carboxyhemoglobin test might be indicated in a pa...

The United States has one of the world's largest per capita fire death rates. House fires alone kill >9,000 Americans annually, and smoke inhalation is the leading cause of mortality from structural fires. Animal models are needed to develop therapies to combat this problem. We have developed a murine model of smoke inhalation through the design, construction, and use of a controlled-environmen...

INTRODUCTION The objective of the paper was the presentation of observations and conclusions based on the review of autopsy records collected at the Department of Forensic Medicine, Medical University of Białystok in the years 2004-2006. MATERIAL AND METHODS The criteria under evaluation included sex, age, alcohol level, carboxyhemoglobin concentration and site of poisoning. The COHb level wa...