Polypyrrole (PPy) was chemically synthesised at two pH levels (pH = 2 and unadjusted pH, i.e. 6.6) using pre-formed carboxymethylcelluloseiron (CMC-Fe) complexes. The CMC-Fe complexes were prepared at a fixed CMC concentration, i.e. 5.5x10 mol/L, and with an increasing FeCl3 amount (from 4x10 to 5x10 mol/L). The quantity of iron bound to CMC was determined by the inductively coupled plasma (ICP...

Introduction. Mortality in generalized peritonitis ranges from 16% to 30%.The aim of research was experimentally study the effect immobilized form 0.01% miramistin on basis sodium salt carboxymethylcellulose course inflammatory process purulent peritonitis.Materials and methods. The experimental included 288 male Wistar rats, divided into 3 groups, 96 animals each. Animals 1st group (control) w...

A gene encoding a glycoside hydrolase family 44 (GH44) protein from Clostridium acetobutylicum ATCC 824 was synthesized and transformed into Escherichia coli. The previously uncharacterized protein was expressed with a C-terminal His tag and purified by nickel-nitrilotriacetic acid affinity chromatography. Crystallization and X-ray diffraction to a 2.2-A resolution revealed a triose phosphate i...

The effect of the interaction of iota-carrageenan (ICG) or lambda-carrageenan (LCG) with locust bean gum and carboxymethylcellulose on the properties of ice cream was studied employing a mixture design approach. A model formulation was employed with of 5% (w / w) of hydrocolloids like stabilizers. Hydrocolloids mixture effect on ice cream properties (base viscosity, ice-cream overrun, hardness,...

PURPOSE Artificial tear formulations typically contain a water-soluble polymer to enhance residence time, moisture retention, and binding to the mucin coat of the ocular surface, which facilitate corneal healing. This study investigated the potential advantages of combining carboxymethylcellulose (CMC) and hyaluronic acid (HA) polymers in a single formulation. MATERIALS AND METHODS Individual...

PURPOSE To evaluate the efficacy of a new lubricant eye drop containing polyethylene glycol 400 and propylene glycol demulcents with hydroxypropyl-guar as a gelling agent (Test Product) to a system with carboxymethylcellulose (Control Product) for reducing dry eye signs and symptoms. METHODS Eighty-seven dry eye volunteers were enrolled at seven sites for this six-week, concurrently controlle...

Intralesional triamcinolone acetonide injection is indicated for multiple skin conditions such as keloid scars, alopecia areata, and hypertrophic lichen planus. Immediate hypersensitivity reaction remains uncommon. We report on a 24-year-old woman who had received multiple intralesional injections with triamcinolone acetonide (Kenacort) plus lidocaine for keloid scar treatment without any react...

A mucoadhesive drug delivery system for systemic delivery of nitrendipine, a calcium channel blocker through buccal route was formulated. Mucoadhesive polymers like hydroxypropylmethylcellulose K-100, hydroxypropylcellulose, sodium carboxymethylcellulose, sodium alginate, polyvinyl alcohol, polyvinyl pyrrolidone K-30 and carbopol-934P were used for film fabrication. The films were evaluated for...