Most airlines overbook their actual capacity (for both passengers and cargo) because part of the booked demand often does not show up at the flight departure. A key element of overbooking is a model that accurately predicts the show-up rate of the current bookings. Given the increasing importance of cargo within their business, most major airlines now scrutinize estimates of show-up rates for c...

Ubiquitinated plasma membrane proteins (cargo) are delivered to endosomes and sorted by endosomal sorting complex required for transport (ESCRT) machinery into endosome intralumenal vesicles (ILVs) for degradation. In contrast to the current model that postulates that ILVs form individually from inward budding of the endosomal limiting membrane, plant ILVs form as networks of concatenated vesic...

COPI-coated vesicle budding from lipid bilayers whose composition resembles mammalian Golgi membranes requires coatomer, ARF, GTP, and cytoplasmic tails of putative cargo receptors (p24 family proteins) or membrane cargo proteins (containing the KKXX retrieval signal) emanating from the bilayer surface. Liposome-derived COPI-coated vesicles are similar to their native counterparts with respect ...

How is Ran involved in nuclear transport? Cargo is transported through pores in the nuclear envelope, in association with carriers that bind to pore proteins called nucleoporins. A Ran–GTP gradient across the envelope is created by the asymmetric distribution of the GTPase activating protein known as RanGAP, which is in the cytosol, and of the guanine nucleotide exchange factor RanGEF in the nu...

12 Nervous system function requires intracellular transport of channels, receptors, mRNAs, and other cargo throughout complex neuronal morphologies. Local signals such as synaptic input can regulate cargo trafficking, motivating the leading conceptual model of neuron-wide transport, sometimes called the “sushi-belt model” (Doyle and Kiebler, 2011). Current theories and experiments are based on ...

This paper concentrates on the problem of the air cargo space management strategy with a comprehensive, abstract and simplified way, on the basis of the actual characteristics of transport demand in China's air cargo market. We focus on the urgent transportation of goods and general cargo transport whose time requirements are different. The paper first proposes a single-leg cargo space manageme...

http://www.aic.gov.au Adam Graycar Director Many companies suffer losses through cargo theft, particularly small businesses, yet it is an area of business crime that receives scant attention. A single truckload of cargo can be worth as much as $3 million. The risk of theft, especially if the goods have a black market value, is very real. Worldwide, the direct cost of cargo theft is estimated at...

Plasma membrane proteins that enter cells by clathrin-independent endocytosis (CIE) are sorted either to lysosomes for degradation or recycled back to the plasma membrane. Expression of some MARCH E3 ubiquitin ligases promotes trafficking of CIE cargo proteins to lysosomes by ubiquitylating the proteins. Here, we show that co-expression of the ubiquitin-specific protease TRE17/USP6 counteracts ...