The rates of mental illness, especially anxiety and depression, have increased greatly since the start COVID-19 pandemic. Traditional illness screening instruments are too cumbersome biased to screen an entire population. In contrast, smartphone call text logs passively capture communication patterns thus represent a promising alternative. To facilitate advancement such research, we collect cur...

Feline immunodeficiency virus (FIV) was isolated from a wild-caught Tsushima cat (Felis bengalensis euptilura), an endangered Japanese nondomestic subspecies of leopard cat (F. bengalensis). Phylogenetic analysis of the env gene sequences indicated that the FIV from the Tsushima cat belonged to a cluster of subtype D FIVs from domestic cats. FIVs from both the Tsushima cat and the domestic cat ...

The problems of sphere theorems in Riemannian geometry have yielded the beautiful results and the fruitful techniques for the study of global geometry (cf. [22]). The main purpose of this paper is to study sphere theorems for CAT(1)-spaces: When are CAT(1)-spaces homeomorphic to the sphere? The notion of CAT(κ)-spaces is introduced by Gromov ([11]) based on Alexandrov’s original notion, i.e., s...

As phylogenetic datasets have increased in size, site-heterogeneous substitution models such as CAT-F81 and CAT-GTR have been advocated in favor of other models because they purportedly suppress long-branch attraction (LBA). These models are two of the most commonly used models in phylogenomics, and they have been applied to a variety of taxa, ranging from Drosophila to land plants. However, ma...

Cardiac calcified amorphous tumor (CAT) is a rare nonneoplastic cardiac mass composed of calcium deposits in a background of amorphous degenerating fibrin material. Recently, cardiac CAT has gained considerable attention. A MEDLINE search of studies published until April 2017 using the term “cardiac calcified amorphous tumor” resulted in 54 articles, 49 of which were reported in the last 10 yea...

Stepwise degradation of the invariant chain (Ii) is required for the binding of antigenic peptides to MHC class II molecules. Cathepsin (Cat) L in the murine thymus and Cat S in peripheral APCs have both been implicated in the last step of Ii degradation that gives rise to the class II-associated invariant chain peptides (CLIP). Cat V has been recently described as highly homologous to Cat L an...