Crossed cerebellar diaschisis (CCD) is well described in the chronic phase of stroke, but few data describe acute CCD and its serial changes after reperfusion. Using positron emission tomography (PET), we studied acute CCD with respect to supratentorial perfusion and outcome measures. In 19 acute stroke patients receiving intravenous thrombolysis (<3 h), 15O-water PET assessed CCD and supratent...

The objective of the research is to study and compare response surface designs: Central composite designs (CCD), BoxBehnken designs (BBD), Small composite designs (SCD), Hybrid designs, and Uniform shell designs (USD) over sets of reduced models when the design is in a spherical region for 3 and 4 design variables. The two optimality criteria ( D and G ) are considered which larger values imply...

This research article presents the Quality by Design (QbD)-finalised conditions for a method that uses liquid chromatography-tandem mass spectrometry for the determination of concentration of enzalutamide (ENZ), an atypical anticancer drug, in a drug formulation and in spiked plasma samples. Critical process attributes (CPA) considered to be the influential parameters in separation, identificat...

the aim of this research was to optimize bioremediation of seawater samples spiked with 1000 mg/l crude oil for removal of n-alkanes (c12h26 to c34h70). bioaugmentation experiments were performed at laboratory scale: each bioreactor contained 250 ml dispersed crude-oil-contaminated seawater, indigenous acclimatized microorganism and nitrogen and phosphorus at concentrations based on central com...

Paracrine and autocrine actions of the insulin-like growth factors (IGFs) are inferred by local expression within the bowel. CCD-18Co cells, IEC-6 cells, and immunoneutralization were used to analyze whether IGFs have direct autocrine or paracrine effects on proliferation of cultured intestinal fibroblasts and epithelial cells. Growth factor expression was analyzed by ribonuclease protection as...

Thermal cracking of a heavy liquid hydrocarbon was performed in a laboratory scale tubular reactor. Central Composite Design (CCD), was used as an experimental design method. The design variables were Coil Outlet Temperature (COT), feed flow and rate steam ratio. Maximum yield of ethylene was 30.37 wt% at COT, residence time and steam ratio of 869oC, 0.208 s and 1.22 g/g, respect...

objective: after introduction of digital radiography into dentistry several methods of image acquisition were accessible in the field of dentistry. in many instances it is necessary to digitize analog images. there is no overall acceptable method for image digitization so all different types of images can be comparable. the objective of this study was to compare the diagnostic accuracy of diffe...

Film scanners will be used for many years to come and it is well known that not even the best and most expensive scanners are not free of errors. Scanner testing and calibration procedures are necessary to achieve a high geometric and radiometric scanner performance. It is also a means to produce or make use of cheaper scanners that do not rely on expensive mechanical positioning and optical pa...

Each CCD is a square 4 megapixel device, with 2048 pixels on each side. Photons impinging on the CCD first pass through an image intensifier. The aperture on the intensifier does not quite cover the entire CCD, instead covering only an “Active Region” that is 1388 x 1516 pixels in size. The CIPS instrument will be capable of telemetering to the spacecraft bus the data from the entire CCD or any...