A 68-year-old man was admitted to our hospital in September 2008 because of a left-sided chest pain. Bone marrow examination showed that 85.5% of leukemic cells were positive for myeloperoxidase (MPO) and were negative for esterase stain. Flow cytometric analysis (FCM) revealed the expression of CD19, CD79a, CD13, CD33, CD34, and HLA-DR on the blasts. Cytogenetic analysis of bone marrow cells u...

An 83-year-old male presented with anorexia, asthenia, weight loss, and profuse sweating. A 2-cm axillary lymphadenopathy and an abdominal mass in the right lower quadrant were palpable. Thoracic and abdominal CT scans were performed (Fig. 1). Colonoscopy revealed numerous sessile, erythematous polyps up to 1 cm in size with a white apex, and also pale, non-adenomatous polyps in the sigmoid and...

Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma (DLBCL) is a rare subtype of non-Hodgkin's lymphoma (NHL) with distinct morphologic and immunohistochemical features. We reported a 57-year-old female with ALK-positive DLBCL in her left nasal cavity. Histologically, the tumor cells were characterized by plasmablastic morphology and tested positive for ALK in a cytoplasmic ...

We report a rare case of non-Hodgkin lymphoma with mass lesions of skull vault and ileocecum. The patient was an 82-year-old Japanese woman who exhibited a painless subcutaneous scalp tumor in the right parietal region associated with no neurological abnormalities. Magnetic resonance imaging of the head demonstrated a mass in the skull vault with iso- to hypointense signals on both T1- and T2-w...

Lymphoma is usually the malignant tumor which originates from lymph node or lymph-tissues. The nasal cavity and paranasal sinuses are rare primary sites for lymphoma. In the paranasal sinuses, lymphoma of maxillary sinuses is the most common, ethmoidal sinuses is more than that of frontal sinuses, sphenoid sinuses is the least. The most common presenting symptoms are nasal obstruction, rhinorrh...

Plasmablastic lymphoma (PBL) is a rare B-cell neoplasm with an aggressive clinical behavior that predominantly occurs in the oral cavity of human immunodeficiency virus (HIV)-positive patients. HIV-negative PBL has not been extensively reported. A 65-year-old female presented with anemia, who was HIV-negative. Gastrointestinal fiberscope (GIF), and colon fiberscope (CF) were performed. However,...

Fetal and adult stem cells have the potential to play vital role in livestock production and management. Fetal stem cells in comparison to stem cells from other sources are easily accessible and can be isolated in larger quantities. Additionally it can provide new insights into development biology of animals. Fetal stem cells may develop as a valuable source of stem cells for clinical applicati...