نتایج جستجو برای: cel 3c

تعداد نتایج: 7961  

2010
Tsung-Yeh Yang Yun-Min Sung Guang-Sheng Lei Tony Romeo Kin-Fu Chak

Carbon storage regulator (CsrA) is a eubacterial RNA-binding protein that acts as a global regulator of many functionally diverse chromosomal genes. Here, we reveal that CsrA represses expression from an extrachromosomal element of Escherichia coli, the lysis gene (cel) of the ColE7 operon (cea-cei-cel). This operon and colicin expression are activated upon SOS response. Disruption of csrA caus...

Journal: :Protein and peptide letters 2009
Keigo Hisamatsu Hideaki Unno Shuichiro Goda Tomomitsu Hatakeyama

The hemolytic lectin CEL-III and its site-directed mutants were expressed in Escherichia coli cells. Replacement of the valine clusters in domain 3 with alanine residues led to increased self-oligomerization in solution and higher hemolytic activity. The results suggest the involvement of these valine clusters in CEL-III oligomerization and hemolytic activity.

2018
Kenneth M McCullough Filomene G Morrison Jakob Hartmann William A Carlezon Kerry J Ressler

Molecular identification and characterization of fear controlling circuitries is a promising path towards developing targeted treatments of fear-related disorders. Three-color in situ hybridization analysis was used to determine whether somatostatin (SOM, Sst), neurotensin (NTS, Nts), corticotropin-releasing factor (CRF, Crf), tachykinin 2 (TAC2, Tac2), protein kinase c-δ (PKC-δ, Prkcd), and do...

Journal: :Journal of lipid research 2002
David Y Hui Philip N Howles

Carboxyl ester lipase (CEL), previously named cholesterol esterase or bile salt-stimulated (or dependent) lipase, is a lipolytic enzyme capable of hydrolyzing cholesteryl esters, tri-, di-, and mono-acylglycerols, phospholipids, lysophospholipids, and ceramide. The active site catalytic triad of serine-histidine-aspartate is centrally located within the enzyme structure and is partially covered...

Journal: :The European respiratory journal 2014
Poornima Gopal Niki L Reynaert Jean L J M Scheijen Lean Engelen Casper G Schalkwijk Frits M E Franssen Emiel F M Wouters Erica P A Rutten

Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation and oxidative stress. These conditions may lead to the formation of advanced glycation end-products (AGEs). In this study we investigated in 88 COPD patients and 55 control subjects (80% ex-smokers) the association of the plasma protein-bound AGEs N(ε)-(carboxymethyl)lysine (CML), pentosidine, N(ε)-(carboxyeth...

2016
Marion A. David Stéphane Orlowski Roger K. Prichard Shaima Hashem François André Anne Lespine

Macrocyclic lactones (ML) are important anthelmintics used in animals and humans against parasite nematodes, but their therapeutic success is compromised by the spread of ML resistance. Some ABC transporters, such as p-glycoproteins (Pgps), are selected and overexpressed in ML-resistant nematodes, supporting a role for some drug efflux proteins in ML resistance. However, the role of such protei...

2016
Wanwitoo Wanmolee Warasirin Sornlake Nakul Rattanaphan Surisa Suwannarangsee Navadol Laosiripojana Verawat Champreda

BACKGROUND Efficient hydrolysis of lignocellulosic materials to sugars for conversion to biofuels and chemicals is a key step in biorefinery. Designing an active saccharifying enzyme system with synergy among their components is considered a promising approach. RESULTS In this study, a lignocellulose-degrading enzyme system of Chaetomium globosum BCC5776 (CG-Cel) was characterized for its act...

ژورنال: :مجله علوم پزشکی رازی 0
فریده قاضی f ghazi دانشیار و دکترای(phd) بیولوژی مولکولی، دانشکده پزشکی، تقاطع بزرگراه شهید همت و چمران، دانشگاه علوم پزشکی و خدمات بهداشتی ـ درمانی ایران، تهرا علی اکبر گرزین a.a gorzin کارشناس ارشد ویروس شناسی. محمود شمس شهرآبادی m shahrabadi استاد و دکترای ویروس شناسی، دانشکده پزشکی، تقاطع بزرگراه شهید همت و چمران، دانشگاه علوم پزشکی و خدمات بهداشتی ـ درمانی ایران، تهران، ایرا� بهاره دبیرمنش b dabirmanesh کارشناس ارشد بیوشیمی.

زمینه و هدف: پاراکوویروس های انسانی، جزء خانواده پیکورنا ویروس ها می باشند که از نظر کلینیکی حائز اهمیت هستند. اخیراً بررسی توالی ژنوم پاراکوویروس تیپ یک نشان داده است که این ویروس، از پیکورنا ویروس های دیگر متفاوت بوده و فاقد موتیفی است که در فعالیت پروتئازی 2a دخالت دارد. هدف از انجام این مطالعه، بررسی فعالیت پروتئولیتیکی پروتئین 3c در پاراکو ویروس انسانی تیپ یک می باشد. روش بررسی: این مطالعه ...

2001
Klaus Rothfels

The technique facilitates karyotype analysis primarily of cel ls grown in vitro Following standard preliminary treatments, the crucial step is the complete air-drying of cel ls on slides directly after fixation. This produces a more complete flattening of intact chromosome complements than is usually achieved manually [The SCI indicates that this paper has been cited in over 510 publications si...

2017
Yichi Zhang Guangming Jin Qianzhong Cao Junxiong Lin Jianqiang Lin Yiyao Wang Su Ern Poh Charlotte Aimee Young Danying Zheng

BACKGROUND Congenital ectopia lentis (CEL) usually leads to refractive error and may influence the axial length development. But few investigations have reported patient demographics and the distribution of axial length (AL) before surgery in Chinese pediatric patients with CEL. To describe the distribution of AL before surgery in CEL patients and its relationship with patients' demographics, s...

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