there exists an association between pi3k pathway licentious activity and the considerable feature of high metastatic potential of the genitourinary cancer cells. although du 145 and 5637 have functional phosphatase and tensin homolog (pten) tumor suppressor gene, which antagonizes pi3k function, pc-3 is null for pten gene. in pursuit to explain why pten bearing cell lines display high metastati...

BACKGROUND AIMS Mesenchymal stromal cells (MSCs) are being extensively researched for cell therapy and tissue engineering. We have engineered MSCs to express the pro-apoptotic protein tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and are currently preparing this genetically modified cell therapy for a phase 1/2a clinical trial in patients with metastatic lung cancer. To do thi...

E-banking (electronic banking) is the modified business banking toward E-business (electronic business) banking that actually uses the electronic communication channels such as internet, phones, cell phones and the like. By using this method, the demands of customers such as time independent and high flexible actions are satisfied. In this process, marketing is so important because guiding cust...

The objective of the study was to compare the sensitivity of wild and laboratory-bred bank voles to cadmium (Cd)-induced histopathological changes in the liver and kidneys. For 4 weeks, the male bank voles-both wild and laboratory-bred-were provided with diet containing Cd in quantities <0.1 (control), 30, and 60 μg/g dry weight. At the end of exposure period, histopathology and analyses of Cd,...

the aim of this research is to classification of soil seed bank in populus caspica protected area. the study of above ground vegetation and soil seed bank were carried out with braun-blanquet and seedling emergence method respectively. results showed that size of soil seed bank in upper layer (713 seeds per m2) were significantly lower than depth layer (1163 per m2) but species richness from 42...

BACKGROUND The hematopoietic stem cell bank has been actively recruiting registrants since 1994. This study systematically reviews its operations and outcomes over the last 20 years. METHODS Retrospective data on a total of 47,711 registrants were reviewed. Relevant data were processed using PASW Statistics for Windows, version 18.0. RESULTS As of 2013, the Korean Network for Organ Sharing ...

river banks are exposed to bank erosion and destruction. one of the river engineering goals is to provide human life requirements and reduce river danger. so spreading extent of this phenomenon, whose risk and other important factors must be recognized. using groins is one of the control ways that by accurate design and accurate performance, bank erosion control and field reclamation would be p...

The functional septo-temporal (dorso-ventral) differentiation of the hippocampus is accompanied by gradients of adult hippocampal neurogenesis (AHN) in laboratory rodents. An extensive septal AHN in laboratory mice suggests an emphasis on a relation of AHN to tasks that also depend on the septal hippocampus. Domestication experiments indicate that AHN dynamics along the longitudinal axis are su...

Here, we present an update of Breast Cancer Now Tissue Bank bioinformatics, a rich platform for the sharing, mining, integration and analysis of breast cancer data. Its modalities provide researchers with access to a centralised information gateway from which they can access a network of bioinformatic resources to query findings from publicly available, in-house and experimental data generated ...

stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. they are found in multicellular organisms. in mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. in ad...