The objective of this work was to improve aqueous solubility of poorly water soluble drugs by a modified porous starch as solid dispersion carrier. The yield of the porous starch was found to be 80%. The flow property of the prepared porous starch was found to be good, with good compressibility index. The particle size of the prepared porous starch were found to be in the range of 53–130μ. Ther...

Porous biomaterials have been widely used as scaffolds in tissue engineering and cell-based therapies. The release of biological agents from conventional porous scaffolds is typically governed by molecular diffusion, material degradation, and cell migration, which do not allow for dynamic external regulation. We present a new active porous scaffold that can be remotely controlled by a magnetic ...

Balloting on a new test method for use in the ranking of porous packaging materials used in sterile packaging applications by their ability to provide bacterial holdout was completed in July 2007 by ASTM International Committee F02 Flexible Barrier Packaging. As a result of this balloting, there is a new test method available for evaluating the barrier capabilities of porous materials intended ...

We evaluated a variety of methods to recover S. aureus from inanimate surfaces. Two contact agar plates and three swab sampling methods were tested on porous and non-porous surfaces and bar soap. The cost and ease of use of each method was also evaluated. S. aureus was recovered using all methods on both porous and non-porous surfaces. S. aureus could not be detected on three of four brands of ...

A novel numerical method is presented for the simulation of flow in porous media, based on a mesoscopic-scale modelling using smoothed particle hydrodynamics. The method is demonstrated to provide encouraging results for both saturated and unsaturated porous media flow. The Darcy law is confirmed for low drift velocities in a saturated medium, while nonlinear behaviour is observed for higher va...

This paper concerns the Stokes flow of an incompressible viscous fluid past a swarm of porous nanocylindrical particles enclosing a solid cylindrical core with Kuwabara boundary condition. An aggregate of porous nanocylindrical particles is considered as a hydro-dynamically equivalent to a solid cylindrical core with concentric porous cylindrical shell. The Brinkman equation inside the porous c...

The multi-sized porous β-tricalcium phosphate scaffolds were fabricated by freeze drying followed by slurry coating using a multi-sized porous sponge as a template. Then, gelatin was dip coated on the multi-sized porous β-tricalcium phosphate scaffolds under vacuum. The mechanical and biological properties of the fabricated scaffolds were evaluated and compared to the uniformly sized porous sca...

Gene delivery from tissue engineering scaffolds can induce localized expression of tissue inductive factors to direct the function of progenitor cells, either endogenous or transplanted. In this report, we developed a layering approach for fabricating scaffolds with encapsulated plasmid, and investigated in vivo gene transfer following implantation into intraperitoneal fat, a widely used site f...

Development of additive manufacturing in last decade greatly improves tissue engineering. During the manufacturing of porous scaffold, simplified but functionally equivalent models are getting focused for practically reasons. Scaffolds can be classified into regular porous scaffolds and irregular porous scaffolds. Several methodologies are developed to design these scaffolds. A novel method is ...

In this study, two-dimensional finite element modeling was used to study the simultaneous effect of the cell shape and regular cell distribution on the anisotropy of the elastic properties of 316L stainless steel foam. In this way, the uniaxial compressive stress-strain curve was predicted using a geometric model and fully solid 316L stainless steel. The results showed that the elastic tangent ...