OBJECTIVES Computerized tomographic angiography (CTA) has emerged as a valuable diagnostic tool for the management of patients with cerebrovascular disease. The use of CTA in lieu of, or as an adjunct to, conventional cerebral angiography in the management of cerebral aneurysms awaits further experience. In this study, we evaluated the role of CTA specifically for the pre-operative assessment a...

A 6-year-old girl presented with a very large aneurysm of the distal branch middle cerebral artery( angular artery). There was previous history mild traumatic brain injury. The presentation happened more than 5 weeks after trauma an atypical visual complaint. She successfully treated by embolization and occlusion parental vessel. Recognizing pos is challenging in young child must be remembered ...

We describe 3 cases with dissecting aneurysm of middle cerebral artery suffered from subarachnoid hemorrhage. Two cases were male and the other was female. All patients presented with headache and/or deterioration of consciousness without any symptom of cerebral ischemia. Angiography disclosed aneurysmal dilatation of M2 or M3 segment of middle cerebral artery with no branching, and in 1 case, ...

BACKGROUND AND PURPOSE The degradation of extracellular matrix (ECM) is a hallmark of a cerebral aneurysm; however, little is known regarding the molecular mechanism leading to this change. Tissue inhibitor of matrix metalloproteinase (TIMP) regulates the ECM degradation in vascular walls by inhibiting the activity of matrix metalloproteinases (MMPs). We investigated the role of TIMPs in the pr...

We report the case of a young woman with a history of cocaine use who presented with subarachnoid hemorrhage secondary to rupture of an aneurysm of the P1 segment of the posterior cerebral artery, treated via intracranial vascular microsurgery. A 29-year-old woman presented with sudden onset of headache, nausea, vomiting, and nuchal rigidity (Hunt & Hess grade II). The patient was a cocaine use...

isolated third nerve palsy develops in numerous intracranial pathologies such as closed head trauma, tumor, and aneurysm. this report describes a 61 years old female with an abrasion on the left forehead and ptosis of the left eye. initial computed tomography did not reveal any causative cerebral and vascular lesions or orbital and cranial fractures. high-resolution and multi-axial enhanced mag...

Drug abuse represents a significant health issue. Evidence suggests that recreational drug use has a direct effect on the cerebral vasculature and is of greater concern in those with undiagnosed aneurysms or vascular malformations. The authors report a case of thunderclap headache with a negative head CT and equivocal lumbar puncture after a drug-fueled weekend. The patient underwent diagnostic...

BACKGROUND Inflammation is a key element behind the pathophysiology of cerebral aneurysm formation and rupture. Aspirin is a potent inhibitor of cyclooxygenase-2 (COX), which plays a critical role in the expression of immune modulators known to contribute to cerebral aneurysm formation and rupture. Currently, there are no pharmacological therapies for patients with cerebral aneurysms. Both endo...

Purpose: Cerebral aneurysms are dilatations of cerebral arteries and result from a local weakness of the vessel wall. They bear a high risk of rupture, leading to intracranial bleedings. Since these structures are parts of a complex vascular system, the adjacent vessels and the aneurysm position convey important contextual information for diagnosis and treatment planning. We concentrate on the ...

Objective and Importance: To describe the clinical presentation and neuropathological findings of metastatic cerebral aneurysms of bronchogenic origin. Metastatic bronchogenic cerebral aneurysms are exceptionally rare and have only been reported in association with high grade hemorrhage. Clinical Presentation: One patient presenting with a history of headache, speech difficulty, left-sided “num...