نتایج جستجو برای: cervical tissue

تعداد نتایج: 996181  

Journal: :Annals of the Academy of Medicine, Singapore 1998
S C Quek T Mould K Canfell A Singer V Skladnev M Coppleson

The Polarprobe is a portable non invasive electronic device designed for the detection of cervical precancer and cancer. It measures both electrical and optical properties of cervical tissue to allow a real time comparison with a databank of previously determined cervical tissue types. The need for additional tests to augment or even replace the Papanicolaou smear has partly prompted its develo...

2015
Shouhua Yang Henghui Cheng Zaiju Huang Xiaoling Wang Yinglu Wan Jing Cai Zehua Wang

OBJECTIVE To investigate soluble neuropilin-1 (sNRP-1) in circulating and NRP-1 protein in cervical tissues from patients with cervical cancer or cervical intraepithelial neoplasia (CIN). METHODS sNRP-1 was measured in 64 preoperative patients and 20 controls. NRP-1 protein in cervical tissue was detected in 56 patients and 20 controls. RESULTS Both sNRP-1 and NRP-1 proteins were correlated...

2014
Azra Kenarkoohi Masoud Soleimani Taravat Bamdad Hoorieh Soleimanjahi Hajar Estiri Mohammad Hadi Razavi-Nikoo

BACKGROUND Although the incidence of cervical cancer has reduced during last years, but it causes mortality among women. Many efforts have performed to develop new drugs and strategy for treatment of cervical cancer. Adipose Tissue-Derived mouse Mesenchymal Stem Cells (MSCs) has many advantages which make them a suitable choice as a cell therapeutic agent in cancer treatment. In this study, we ...

2013
YIJIN SU LIANFANG DU YING WU JUAN ZHANG XUEMEI ZHANG XIAO JIA YINGYU CAI YUNHUA LI JING ZHAO QIAN LIU

The aim of this study was to evaluate the application of acoustic radiation force impulse (ARFI) ultrasound imaging and its potential value in the characterization of cervical cancer. ARFI ultrasound imaging of the uterine cervix was performed in 58 patients with cervical cancer prior to surgery. The diagnosis of cervical cancer was confirmed by pathological results in each case. eSie Touch ela...

Journal: :Epigenetics 2013
Sanja A Farkas Nina Milutin-Gašperov Magdalena Grce Torbjörn K Nilsson

The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical lesions and development of cervical cancer. The DNA methylation signatures of the host genome in normal, precancerous and cervical cancer tissue may indicate tissue-specific perturbation in carcinogenesis. The aim of this study was to identify new candidate genes that are differentially methylated in squamous...

2016
Dongmei Gao Yuanyuan Zhang Mingyue Zhu Shuang Liu Xinling Wang

The study aimed to investigate the state of human papillomavirus (HPV) infection in patients with cervical cancer in the Uyghur population in China and to identify miRNA as biomarker for cervical cancer and HPV infection. We also performed genotyping to determine the variation in the types of HPV. Using microRNA (miRNA) microarray technology, differential miRNA expression between HPV-infected c...

Journal: :European review for medical and pharmacological sciences 2017
F-L Wang Y Yang Z-Y Liu Y Qin T Jin

OBJECTIVE To study the methylation of the promoter of the p16 gene in cervical cancer patients and explore the correlation between methylation and the incidence of cervical cancer. PATIENTS AND METHODS We recruited 78 patients with cervical cancer and 48 healthy individuals. The methylation-specific PCR was used to detect the methylation status in the promoter of the p16 gene. The mRNA expres...

Journal: :Pathobiology : journal of immunopathology, molecular and cellular biology 2011
Mohammed Shaker Yuhki Yokoyama Seiji Mori Masahiko Tsujimoto Naomasa Kawaguchi Tohru Kiyono Toru Nakano Nariaki Matsuura

OBJECTIVE Dysregulated expression of disintegrin-metalloprotease proteins [a disintegrin and metalloproteases (ADAMs) and ADAMs with thrombospondin motif (ADAMTSs)] has been reported in many types of cancers and is believed to play an important role in cancer formation and metastasis. However, little is known about the expression of ADAMs and ADAMTSs in the development of human cervical cancer....

2013
RS Samson O Ciccarelli C Kachramanoglou L Brightman A Lutti DL Thomas N Weiskopf CAM Wheeler-Kingshott

The aim of this study was to quantify a range of MR parameters [apparent proton density, longitudinal relaxation time T1, magnetisation transfer (MT) ratio, MT saturation (which represents the additional percentage MT saturation of the longitudinal magnetisation caused by a single MT pulse) and apparent transverse relaxation rate R2*] in the white matter columns and grey matter of the healthy c...

Journal: :Experimental and molecular pathology 2014
Nosheen Rashid Haq Nawaz Kelvin W C Poon Franck Bonnier Salih Bakhiet Cara Martin John J O'Leary Hugh J Byrne Fiona M Lyng

Cervical cancer is the third most common cancer affecting women worldwide. The mortality associated with cervical cancer can, however, be significantly reduced if the disease is detected at the pre-malignant stage. The aim of this study was to evaluate the potential of Raman microspectroscopy for elucidation of the biochemical changes associated with the pre-malignant stages of cervical cancer....

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