Principal components analysis (PCA) of face images is here related to subjects' performance on the same images. In two experiments subjects were shown a set of faces and asked to rate them for distinctiveness. They were subsequently shown a superset of faces and asked to identify those that had appeared originally. Replicating previous work, we found that hits and false positives (FPs) did not ...

Percolator is a widely used software tool that increases yield in shotgun proteomics experiments and assigns reliable statistical confidence measures, such as q values and posterior error probabilities, to peptides and peptide-spectrum matches (PSMs) from such experiments. Percolator's processing speed has been sufficient for typical data sets consisting of hundreds of thousands of PSMs. With o...

Macaque monkeys were trained to recognize the repetition of one of the images already seen in a sequence of random length. On average, performance decreased with sequence length. However, this was due to a complex combination of factors, as follows: performance was found to decrease with the separation in the sequence of the test (repetition image) from the cue (its first appearance in the sequ...

The variance components models for gene-environment interaction proposed by Purcell in 2002 are widely used. In both the bivariate and the univariate parameterization of these models, the variance decomposition of trait T is a function of moderator M. We show that if M and T are correlated, and moderator M is correlated between twins as well, the univariate parameterization produces a considera...

Statistical analysis of a data set typically involves testing not just a single hypothesis, but rather many (often very many!). For any particular test, we may assign a pre-set probability α of a type-1 error (i.e., a false positive, rejecting the null hypothesis when in fact it is true). The problem is that using a (say) value of α = 0.05 means that roughly one out of every twenty such tests w...

How does a cell respond to numerous external stresses with a limited number of internal molecular components? It has been observed that there are some common responses of yeast to various stresses, but most observations were based on gene-expression profiles and only some part of the common responses were intensively investigated. So far there has been no system-level analysis to identify commo...

Abstract Inspired by the use of rift-sawn softwood board for covering curved surfaces in Kokerabuki, a traditional Japanese roofing method, we investigated flexural anisotropy wood caused its end-grain orientation. We measured displacement species, Chamaecyparis obtusa and Cryptomeria japonica , hardwood Populus suaveolens Cerasus serrulata . For this was approximately five times longer specime...

When testing multiple hypothesis in a survey –e.g. many different source locations, template waveforms, and so on– the final result consists in a set of confidence intervals, each one at a desired confidence level. But the probability that at least one of these intervals does not cover the true value increases with the number of trials. With a sufficiently large array of confidence intervals, o...

Alex Pokorny's 1983 prospective study of suicide found that 96.3% of high-risk predictions were false positives, and that more than half of the suicides occurred in the low-risk group and were hence false negatives. All subsequent prospective studies, including the recent US Army Study To Assess Risk and Resilience in Servicemembers (STARRS), have reported similar results. We argue that since r...