A result of the increased usage of advanced high strength steels (AHSS) for stamped automotive body structures is an increase in press forces and tool wear, as well as component geometrical issues, such as springback and curl. This study investigates a methodology of forming a dual-phase steel component in a ‘softened’, or annealed, condition, then subsequently heat-treating and quenching the c...

This paper shows the capability the alternating direction method of multipliers (ADMM) has to track, in a distributed manner, the optimal down-link beam-forming solution in a multiple input multiple output (MISO) multi-cell network given a dynamic channel. Each time the channel changes, ADMM is allowed to perform one algorithm iteration. In order to implement the proposed scheme, the base stati...

determination of the deformation length is one of the first steps in roll forming design. roll forming industries are very interested in explicit simple relationsfor prediction the deformation length without using trail-and-error methods at workshop or time consuming finite element simulations. in this paper, elastic properties and work-hardening behaviour of the strip are considered in additio...

We identified a consensus N-linked glycosylation motif within the pore-forming loop between the fifth and sixth transmembrane segments of the osmoresponsive transient receptor potential (TRP) channel TRPV4. Mutation of this residue from Asn to Gln (i.e., TRPV4(N651Q)) resulted in loss of a slower migrating band on anti-TRPV4 immunoblots and a marked reduction in lectin-precipitable TRPV4 immuno...

We report that long-chain poly-L-glutamine forms cation-selective channels when incorporated into artificial planar lipid bilayer membranes. The channel was permeable to alkali cations and H(+) ions and virtually impermeable to anions; the selectivity sequence based on the single-channel conductance was H(+) >> Cs(+) > K(+) > Na(+). The cation channel was characterized by long-lived open states...

III-V-on-nothing (III-VON) metal-oxide-semiconductor field-effect transistors (MOSFETs) are experimentally demonstrated with In0.53Ga0.47As as channel and atomic layer deposited Al2O3 as gate dielectric. A hydrochloric acid based release process has been developed to create an air gap beneath the InGaAs channel layer, forming the nanowire channel with width down to 40 nm. III-VON MOSFETs with c...

Tight regulation of calcium entry through the L-type calcium channel CaV1.2 ensures optimal excitation-response coupling. In this issue of Neuron, Michailidis et al. (2014) demonstrate that CaV1.2 activity triggers negative feedback regulation through proteolytic cleavage of the channel within the core of the pore-forming subunit.

The pore-forming subunits of canonical voltage-gated sodium and calcium channels are encoded by four repeated domains of six-transmembrane (6TM) segments. We expressed and characterized a bacterial ion channel (NaChBac) from Bacillus halodurans that is encoded by one 6TM segment. The sequence, especially in the pore region, is similar to that of voltage-gated calcium channels. The expressed cha...