Cefpodoxime Proxetil (Poorly water soluble drug), when prepared as solid dispersion showed improved solubility and dissolution. So the main purpose of this investigation was to increase the solubility and dissolution rate of Cefpodoxime Proxetil by the preparation of its solid dispersion with urea using solvent evaporation method. Physical mixtures and solid dispersions of Cefpodoxime Proxetil ...

Stable dispersion of reduced graphene in various organic solvents was achieved via noncovalent functionalization with amine-terminated polymers. An aqueous dispersion of reduced graphene was prepared by chemical reduction of graphene oxide in aqueous media and was vacuum filtered to generate reduced graphene sheets. Good solvents and nonsolvents for the dried reduced graphene were evaluated usi...

We present a computational analysis of the terahertz spectra of the monoclinic and the orthorhombic polymorphs of 2,4,6-trinitrotoluene. Very good agreement with experimental data is found when using density functional theory that includes Tkatchenko-Scheffler pair-wise dispersion interactions. Furthermore, we show that for these polymorphs the theoretical results are only weakly affected by ma...

GAIA spectroscopic and radial velocity performancies are reviewed on the base of groundbased test observations and simulations. The prospects for accurate analysis of stellar atmospheres (temperature, gravity, chemical abundances, rotation, peculiarities) and precise radial velocities (single stars, binaries, pulsating stars) are colorful provided the spectral dispersion is high enough. A highe...

Purpose: To evaluate the physicochemical properties of clotrimazole (CLT) solid dispersion with Pluronic F127 (PLU). Methods: Solid dispersions of the antifungal drug, clotrimazole, were prepared with Pluronic F127 using grinding (PM) and fusion (FUS) methods. Physicochemical characterization of the dispersions were performed using differential scanning calorimetry (DSC), x-ray powder diffracti...

Analytical solution of dispersion in rapidly oscillating flows becomes infeasible in complex geometries. Simulation over long durations can be prohibitively expensive when there is a wide separation between the oscillation and dispersion time scales. Here, we present a methodology based on an implicit envelope-tracking scheme coupled with telescopic projections. A test problem, with a known ana...

We present the combination of a state control and shape design approaches for the optimization of micro-fluidic channels used for sample extraction and separation of chemical species existing in a buffer solution. The aim is to improve the extraction and identification capacities of electroosmotic micro-fluidic devices by avoiding dispersion of the extracted advected band. Résumé. Nous présento...

Polydopamine is a bioinspired, versatile material that can adhere to bulk and nanoscale surfaces made of disparate materials to improve their physical and chemical properties in many applications. The typical methods to coat polydopamine on the nanoparticle substrates usually take several hours to a day. This work successfully applies a dispersion method to form a controllable, uniform coating ...

Article history: Received 7 April 2011 Received in revised form 17 September 2011 Accepted 18 September 2011 Is wind direction an adequate marker of air mass history? This review looks at the evolution of methods for assessing the effect of the origin and pathway of air masses on composition change and trends. The composition of air masses and how they evolve and the changing contribution of so...

We study the behavior of the pion dispersion relation in a pion medium at finite density and temperature, introducing a chemical potential to describe the finite pion number density. Such description is particularly important during the hadronic phase of a relativistic heavy-ion collision, between chemical and thermal freeze-out, where the pion number changing processes, driven by the strong in...