PEDIATRICS Vol.53 No.4ApriI 1974 for all. Its very emergency nature may at times add trouble since the tendency may be to overdose. It should be kept in mind that harm can be done by overtreating a patient in status epilepticus, particularly when using the longer-acting drugs. The comatose state frequently accompanying status epilepticus can be worsened by the cumulative effect of too frequent ...

The epilepsies are a heterogeneous group of disorders with many causes. However, a genetic aetiology may be present in up to 40% of patients, and this proportion is even higher in epilepsy of childhood onset. The past decade has seen spectacular advances in our understanding of the genetics of epilepsy at a molecular level, and several comprehensive reviews are available. 3 It is apparent that ...

PURPOSE OF REVIEW This article outlines a diagnostic and management approach to pediatric seizures and epilepsy syndromes, and delineates pharmacologic and nonpharmacologic treatment options. RECENT FINDINGS Progress in tracking of seizures, identifying and addressing medication nonadherence, treatment with novel devices, and clinical decision support algorithms will provide additional manage...

BDOMINAL pain is a very common symptom to tile physician who deals with infants, children and adolescents. Intraabdominal conditions such as appendicitis, intussusception, Meckel’s diverticulum, mesenteric adenitis, and kidney disease must be considered as organic causes of pain. Tile onset of acute infectious disease, such as rheumatic fever, pneumonia, hepatitis, and! pancreatitis, also must ...

how to cite this article: mollamohammadi m, tonekaboni sh, pirzadeh z, vahedian m . pregabalin in childhood epilepsy: a clinical trialiran j child neurol. 2014 autumn;8(4): 62-65. abstract objective the prevalence of active epilepsy is about 0.5–1%, and approximately 70% of patients are cured with first anti-epileptic drugs and the remaining patients need multiple drugs. pregabalin as an add-on...

1. Summary statement of the proposal for inclusion, change or deletion Phenytoin base (as EpanutinR) is available as 50mg chewable tablets and an oral suspension of strength 30mg/5ml, and are proposed for addition to the Model List of Essential Medicines, for use in the management of epilepsy in children. It is at least as effective as carbamazepine, phenobarbitone and sodium valproate in the m...

PURPOSE To evaluate the demographic and clinical manifestations and postsurgical outcome of childhood-onset mesial temporal sclerosis and temporal lobe epilepsy (MTS-TLE) and establishing the potential differences as compared to the patients with adult-onset MTS-TLE. METHOD In this retrospective study all patients with a clinical diagnosis of medically refractory TLE due to mesial temporal sc...

BACKGROUND AND AIMS The ketogenic diet is an effective medical therapy for intractable childhood epilepsy. However, it has drawbacks in that it restricts calories, fluids and protein. The Atkins diet may also induce ketosis without those restrictions. Our objective was to evaluate the efficacy of a modified Atkins diet in children with intractable childhood epilepsy. METHODS This clinical tri...

BACKGROUND Neurological soft signs preceding adult-onset schizophrenia suggest a neurodevelopmental origin and could reflect physical illness in childhood. AIMS To investigate possible associations of adult-onset psychosis with neurological soft signs and common infectious illnesses in childhood. METHOD Using data from the UK National Child Development Study, a longitudinal general populati...

RATIONALE Dysembryoplastic neuroepithelial tumors (DNET) are benign, localized lesions that typically cause localization-related epilepsy of childhood onset. Although excellent seizure outcomes are expected following surgical resection of focal, benign lesions, reports in pediatric epilepsy series suggest that this may not be the case with DNETs, which may exhibit complex and often multifocal e...