We prove the following Main Theorem: ZF + AD + V L(R) =>DC. As a corollary we have that Con(ZF + AD) Con(ZF + AD + DC). Combined with the result of Woodin that Con(ZF + AD) Con(ZF + AD + AC') it follows that DC (as well as AC') is independent relative to ZF + AD. It is finally shown (jointly with H. Woodin) that ZF + AD + DCR, where DCR is DC restricted to reals, implies the consistency of ZF +...

Anthracycline antibiotics like doxorubicin (DOX) are known to exert their antitumor effects primarily via DNA intercalation and topoisomerase II inhibition. By contrast, the noncross-resistant cytoplasmically localizing DOX analogue, N-benzyladriamycin-14valerate (AD 198), only weakly binds DNA and does not inhibit topoisomerase II, yet it displays superior antitumor activity, strongly suggesti...

BACKGROUND Atopic dermatitis (AD) and psoriasis represent polar immune diseases. AD is a T(H)2/T(H)22-dominant disease, whereas psoriasis is considered a T(H)1/T(H)17 disease. Local immune deviation is suggested to be regulated by dendritic cell (DC)-induced T-cell polarization and recruitment of specific T-cell subsets by chemokines. Although the role of chemokines is well documented, the actu...

background and objective: alzheimer’s disease (ad) is a multifactorial disease with debilitating consequences and few therapeutic strategies exist for it. with regard to antioxidant capacity and anti-β-amyloid polymerization potential of ellagic acid, this study was conducted to evaluate the effect of this substance on enhanced acetylcholinesterase reactivity in an experimental model of alzheim...

Abstract In this note, we study in a finite dimensional Lie algebra $${\mathfrak g}$$ g the set of all those elements x for which closed convex hull adjoint orbit contains no affine lines; particular whose orbits generates pointed cone $$C_x$$ C x . Ass...

BACKGROUND Alzheimer disease (AD) is under substantial genetic influence. To better understand the genetic influence on component phenotypes of AD, we estimated the heritability (h(2)) of abstract reasoning and examined its relation with apolipoprotein epsilon 4 (APOE-epsilon 4). METHODS We studied abstract reasoning in 1,116 individuals from 210 Caribbean Hispanic families with late onset AD...

OBJECTIVES This paper evaluates the nutritional status in patients with mild-moderate and severe Alzheimer's disease (AD) by bioelectrical impedance vector analysis (BIVA). DESIGN Cross-sectional study. SETTING Alzheimer Center, SS. Trinita Hospital, Cagliari, and "Monsignor Angioni" Nursing Home, Quartu Sant'Elena (Cagliari, Italy). PARTICIPANTS 83 free-living patients with mild-moderate...

Tipe 2 chain A and H antigens qf' human erythrocytes Results of previous studies from our laboratories on the isolation and characterization of erythrocyte glycolipids with blood group A and B activities can be summarized as follows: ( I ) Four A-active and four H-active glycosphingolipid components, termed A", Ah, A , Ad, and H I , H,, H, and H,, have been isolated and their structures have be...

The present study investigated the molecular mechanism of apoptosis and autophagy in prostate epithelial cells under androgen deprivation (AD). BPH-1 cells were divided into four groups as follows: Control (Cont), AD, autophagy inhibition (AI) and AD + AI groups. Cells in the four groups were treated accordingly, and the level of apoptosis was subsequently measured via flow cytometry. The expre...

The 4 original papers are 1. Larsen AD, Hannerz H, Obel C, Thulstrup AM, Bonde JP, Hougaard KS: Testing the association between psychosocial job strain and adverse birth outcomes design and methods. BMC Public Health 2011, 11: 255. 2. Larsen AD, Hannerz H, Juhl M, Obel C, Thulstrup AM, Bonde JP, Hougaard KS: Psychosocial job strain and risk of adverse birth outcomes: a study within the Danish n...