Hepatitis C (HCV) is now the main cause of chronic hepatic disease, cirrhosis and hepatocellular carcinoma. Several extrahepatic diseases have been associated with chronic HCV infection, and in most cases appear to be directly related to the viral infection. Thyroid disorders are common in patients with chronic HCV. Some patients with chronic hepatitis C experience thyroid problems, and thyroid...

Chronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and some systemic autoimmune diseases, especially Sjögren's syndrome, but also rheumatoid arthritis an...

CHRONIC HEPATITIS C VIRUS (HCV) infection is a common worldwide problem. The infection may progress to cirrhosis with the subsequent development of complications such as ascites, encephalopathy, variceal bleeding, and hepatocellular carcinoma. Thus, early detection and therapy is of great importance. There has been substantial progress in understanding various aspects of HCV infection, includin...

Hepatitis C virus (HCV) causes chronic systemic infection, primarily affecting the liver. Although HCV mainly causes hepatitis, a significant portion of chronic HCV patients manifests with at least 1 extrahepatic involvement during the course of their illness. Chronic HCV infection can cause various types of renal diseases. The most common renal manifestations of HCV infection are essential mix...

Introduction. In Poland, approximately 2% of the total population is infected with hepatitis C virus (HCV) (estimated at 730,000 people). HCV an etiologic factor chronic C. Hepatitis a disease which, when untreated, may lead to cirrhosis liver and/or primary cancer. 
 Objective. The aim study was analysis personal medical history patient hepatocellular cancer from aspect infection HCV.&#x0...

Complications involving the central nervous system in patients suffering from hepatitis C virus (HCV) infection have been rare. Among them, it appears the transverse myelitis, which has already been reported in likely association with HCV. This paper presents the case study of a 65-year-old woman who developed cervical transverse myelitis linked to chronic HCV infection and anti-HCV antibodies ...

conclusions our study suggested that the prevalence rate of hepatitis c virus is below 1% in the general population of mashhad. results in this study the overall seroprevalence of hepatitis c was founded to be 0.2% by using elisa method. however, the overall hepatitis c virus infection prevalence was found to be 0.13% with rt-pcr method. patients and methods three thousand, eight hundred and se...

Abstract Globally, approximately 1.5 million new Hepatitis C virus (HCV) infections occur annually. A vaccine to prevent chronic HCV infection would limit transmission and pathogenesis of HCV. To understand immunity in high risk populations, we prospectively followed antibody negative high-risk people who inject drugs (PWIDs) a protocol designed for monthly follow-up. We demonstrated previously...

Frequently, patients with hepatitis C virus (HCV) chronic infection have high levels of serum anti-thyroperoxidase and/or anti-thyroglobulin autoantibodies, ultrasonographic signs of chronic autoimmune thyroiditis, and subclinical hypothyroidism, in female gender versus healthy controls, or hepatitis B virus infected patients. In patients with "HCV-associated mixed cryoglobulinemia" (MC + HCV),...

Antiviral cytotoxic T lymphocytes (CTL) may play a role in clearance of hepatitis C virus (HCV)-infected cells and thereby cause hepatocellular injury during acute and chronic HCV infection. The aim of this study was to identify HLA-A2.1-restricted HCV T-cell epitopes and to evaluate whether anti-HCV-specific CTL are present during chronic hepatitis C. Peripheral blood mononuclear cells from fo...