introduction: corticosteroids are routinely used in management of chronic obstructive pulmonary disease (copd) exacerbation. the main purpose of present study was to compare the efficacy of methyl prednisolone (mp) and dexamethasone (dxm) for this purpose. methods: adult copd patients entered the present clinical trial. all patients received standard treatment on admission and were then divided...

introduction and aims: microscopic colitis has been generally recognized as lymphocytic colitis and collagenous colitis: two inflammatory diseases of large intestine without a definite origin. the colon appears normal by colonoscopy. so, biopsy of the colonic mucosa is mandatory for diagnosis. materials and methods: as a descriptive design we assessed epidemiological, clinical and laboratory fi...

as the world’s population continues to age, practitioners encounter increasing numbers of older patients with end-stage renal disease (esrd) who require renal replacement therapy (rrt). conservative management may be considered in older patients and has been shown to offer comparable survival rates and hospital-free days to rrt patients. at present, for those who choose rrt, hemodialysis is the...

conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...

Background: Sulfur mustard is one of the chemical warfare gases that has been known as a vesicant or blistering agents. It is a chemical alkylating compound agent that can be frequently absorbed through skin, respiratory system, genital tract, and ocular system. This study was done to pathologically analyze the microscopic pancreatic lesions in cadavers. Methods: This case series study was per...

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...

in this study, we report a mutation in cybb gene in a patient with x-cgd (diagnosed on the base of family history, ndt test, dhr 123 assay). mutation in cybb gene was detected using sscp analysis (single-strand conformation polymorphism) followed by sequencing. during screening for mutations in the cybb gene we observed 880 c t in exon 8. this mutation resulted in 290 arg stop. we also observed...